| Literature DB >> 12121957 |
Rémy Durand1, Virginie Huart, Sayeh Jafari, Jacques Le Bras.
Abstract
A PCR-based technique using molecular beacons was developed to detect the chloroquine resistance-associated pfcrt K76T point mutation in Plasmodium falciparum. One hundred thirty African clinical isolates were tested by the new method in comparison with the PCR-restriction fragment length polymorphism method. This rapid and inexpensive genomic assay could expand the possibilities for monitoring chloroquine resistance.Entities:
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Year: 2002 PMID: 12121957 PMCID: PMC127343 DOI: 10.1128/AAC.46.8.2684-2686.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191