Literature DB >> 12121718

Central role of peroxisomes in isoprenoid biosynthesis.

Werner J Kovacs1, Lisa M Olivier, Skaidrite K Krisans.   

Abstract

Peroxisomes contain enzymes catalyzing a number of indispensable metabolic functions mainly related to lipid metabolism. The importance of peroxisomes in man is stressed by the existence of genetic disorders in which the biogenesis of the organelle is defective, leading to complex developmental and metabolic phenotypes. The purpose of this review is to emphasize some of the recent findings related to the localization of cholesterol biosynthetic enzymes in peroxisomes and to discuss the impairment of cholesterol biosynthesis in peroxisomal deficiency diseases.

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Year:  2002        PMID： 12121718     DOI： 10.1016/s0163-7827(02)00002-4

Source DB:  PubMed          Journal:  Prog Lipid Res        ISSN： 0163-7827            Impact factor:   16.195


  36 in total

1.  Peroxisome biogenesis and function.

Authors:  Navneet Kaur; Sigrun Reumann; Jianping Hu
Journal:  Arabidopsis Book       Date:  2009-09-11

Review 2.  The peroxisome: an update on mysteries.

Authors:  Markus Islinger; Sandra Grille; H Dariush Fahimi; Michael Schrader
Journal:  Histochem Cell Biol       Date:  2012-03-14       Impact factor: 4.304

3.  C22-bronchial and T7-alveolar epithelial cell lines of the immortomouse are excellent murine cell culture model systems to study pulmonary peroxisome biology and metabolism.

Authors:  Srikanth Karnati; Saranya Palaniswamy; Mohammad Rashedul Alam; Gani Oruqaj; Cordula Stamme; Eveline Baumgart-Vogt
Journal:  Histochem Cell Biol       Date:  2015-12-21       Impact factor: 4.304

4.  Subcellular localization of Arabidopsis 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Authors:  Pablo Leivar; Víctor M González; Susanna Castel; Richard N Trelease; Carmen López-Iglesias; Montserrat Arró; Albert Boronat; Narciso Campos; Albert Ferrer; Xavier Fernàndez-Busquets
Journal:  Plant Physiol       Date:  2004-12-23       Impact factor: 8.340

5.  Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes.

Authors:  Maya Sapir-Mir; Anahit Mett; Eduard Belausov; Shira Tal-Meshulam; Ahuva Frydman; David Gidoni; Yoram Eyal
Journal:  Plant Physiol       Date:  2008-11       Impact factor: 8.340

6.  ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis.

Authors:  Jinjiang Fan; Xinlu Li; Leeyah Issop; Martine Culty; Vassilios Papadopoulos
Journal:  Mol Endocrinol       Date:  2016-05-11

7.  Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice.

Authors:  Werner J Kovacs; Khanichi N Charles; Katharina M Walter; Janis E Shackelford; Thomas M Wikander; Michael J Richards; Steven J Fliesler; Skaidrite K Krisans; Phyllis L Faust
Journal:  Biochim Biophys Acta       Date:  2012-03-13

8.  Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease.

Authors:  Je-Seong Won; Jinsu Kim; Manjeet Kaur Paintlia; Inderjit Singh; Avtar K Singh
Journal:  Brain Res       Date:  2013-02-21       Impact factor: 3.252

Review 9.  Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.

Authors:  Behzad Yeganeh; Emilia Wiechec; Sudharsana R Ande; Pawan Sharma; Adel Rezaei Moghadam; Martin Post; Darren H Freed; Mohammad Hashemi; Shahla Shojaei; Amir A Zeki; Saeid Ghavami
Journal:  Pharmacol Ther       Date:  2014-02-26       Impact factor: 12.310

10.  Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast.

Authors:  Qian Lu; Karyl I Minard; Lee McAlister-Henn
Journal:  Arch Biochem Biophys       Date:  2008-02-06       Impact factor: 4.013
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