Literature DB >> 12121281

The interleukin-1 receptor antagonist gene: a single-copy variant of the intron 2 variable number tandem repeat (VNTR) polymorphism.

J E Vamvakopoulos1, C J Taylor, G J Morris-Stiff, C Green, S Metcalfe.   

Abstract

A variable number tandem repeat (VNTR) polymorphism exists within intron 2 of the human interleukin-1 receptor antagonist gene, consisting of perfect repeats of an 86-bp sequence. Five allelic variants have been identified wherein the number of repeats varies from two to six. This is the first report of a rare, single-copy allele designated IL1RN*0.

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Year:  2002        PMID: 12121281     DOI: 10.1046/j.1365-2370.2002.00319.x

Source DB:  PubMed          Journal:  Eur J Immunogenet        ISSN: 0960-7420


  13 in total

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10.  Combined association analysis of interleukin 1-receptor antagonist (IL-1RN) variable number of tandem repeat (VNTR) and Haptoglobin 1/2 polymorphisms with type 2 diabetes mellitus risk.

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