Literature DB >> 12121279

CD80 (B7-1) and CD86 (B7-2) genes and genetic susceptibility to coeliac disease.

N Woolley1, P Holopainen, C Bourgain, K Mustalahti, P Collin, M Mäki, J Partanen.   

Abstract

The role of the costimulatory molecules B7-1 (CD80) and B7-2 (CD86) in T-cell activation makes them good candidates for coeliac disease susceptibility genes. We conducted a genetic linkage study of the CD80/86 gene region in the general Finnish population and in a local subisolate. No linkage was found in either population.

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Year:  2002        PMID: 12121279     DOI: 10.1046/j.1365-2370.2002.00302.x

Source DB:  PubMed          Journal:  Eur J Immunogenet        ISSN: 0960-7420


  1 in total

Review 1.  T cell costimulation and coinhibition: genetics and disease.

Authors:  Lisa Scandiuzzi; Kaya Ghosh; Xingxing Zang
Journal:  Discov Med       Date:  2011-08       Impact factor: 2.970

  1 in total

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