OBJECTIVE: Preschizophrenic children who merit psychiatric referral are claimed to have a particularly malevolent illness when the psychosis develops later. The 21 years outcome of a sample of such children was investigated. METHOD: Fifty-one children who attended psychiatric services, and were later diagnosed as having schizophrenia, were followed up a mean of 21 years later. Baseline childhood demographic, clinical and putative aetiological characteristics were identified from the case notes. Follow-up assessment evaluated clinical symptoms, social functioning and service utilization. The predictive value of baseline factors on outcome was examined. RESULTS: Outcome was poor, and seven (14%) of the subjects were deceased. Childhood IQ was strongly predictive of social outcome (F=5.1, P=0.01) and service utilization (F=5.2, P=0.01), but not clinical symptoms. No other factors predicted outcome. CONCLUSION: Low childhood IQ had an unfavourable impact on social outcome and service utilization once schizophrenia developed.
OBJECTIVE: Preschizophrenic children who merit psychiatric referral are claimed to have a particularly malevolent illness when the psychosis develops later. The 21 years outcome of a sample of such children was investigated. METHOD: Fifty-one children who attended psychiatric services, and were later diagnosed as having schizophrenia, were followed up a mean of 21 years later. Baseline childhood demographic, clinical and putative aetiological characteristics were identified from the case notes. Follow-up assessment evaluated clinical symptoms, social functioning and service utilization. The predictive value of baseline factors on outcome was examined. RESULTS: Outcome was poor, and seven (14%) of the subjects were deceased. Childhood IQ was strongly predictive of social outcome (F=5.1, P=0.01) and service utilization (F=5.2, P=0.01), but not clinical symptoms. No other factors predicted outcome. CONCLUSION: Low childhood IQ had an unfavourable impact on social outcome and service utilization once schizophrenia developed.
Authors: Eduardo García-Laredo; Fernando Maestú; Miguel Ángel Castellanos; Juan D Molina; Elisa Peréz-Moreno Journal: Medicine (Baltimore) Date: 2015-09 Impact factor: 1.817
Authors: Irina Rannikko; Graham K Murray; Pauliina Juola; Henri Salo; Marianne Haapea; Jouko Miettunen; Juha Veijola; Jennifer H Barnett; Anja P Husa; Peter B Jones; Marjo-Riitta Järvelin; Matti Isohanni; Erika Jääskeläinen Journal: Schizophr Res Cogn Date: 2015-09-09