Literature DB >> 12120807

Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.

A J P Francis1, R J W Dempster.   

Abstract

Serious sleep problems are common in children with an intellectual deficit (ID), and are often the source of much distress for both the child and caregivers. As yet, no satisfactory long-term treatment exists for intransigent sleep difficulties in children with an ID. Valerian, Valeriana spp., has been used for thousands of years to induce relaxation and sleep. Scientific investigation of valerian's sleep promoting ability in humans, whilst limited, has yielded promising findings. This initial study aimed to explore valerian's potential for assisting in the treatment of sleep problems in children with an ID. Five children with varying intellectual deficits and different primary sleep problems underwent eight continuous weeks of monitoring via sleep diaries, adhering to a double blind, placebo controlled and randomised design. Compared to baseline and placebo, valerian treatment led to significant reductions in sleep latencies and nocturnal time awake, lengthened total sleep time and improved sleep quality. The treatment was apparently most effective in children with deficits that involved hyperactivity. Although the findings are preliminary and in need of replication, there is evidence to suggest that valerian may be useful in the safe and effective long-term treatment of intransigent sleep difficulties in children with ID's, and therefore warrants further investigation.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12120807     DOI: 10.1078/0944-7113-00110

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  5 in total

Review 1.  Valerian for sleep: a systematic review and meta-analysis.

Authors:  Stephen Bent; Amy Padula; Dan Moore; Michael Patterson; Wolf Mehling
Journal:  Am J Med       Date:  2006-12       Impact factor: 4.965

Review 2.  Insomnia: the Sleeping Giant of Pediatric Public Health.

Authors:  Emily Badin; Cynthia Haddad; Jess Parker Shatkin
Journal:  Curr Psychiatry Rep       Date:  2016-05       Impact factor: 5.285

3.  Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice.

Authors:  Jeong Suk Kim; Jeong Deok Ahn; Su-In Cho
Journal:  Pharmacogn Mag       Date:  2015 Apr-Jun       Impact factor: 1.085

4.  Outcome domains and outcome measures used in studies assessing the effectiveness of interventions to manage non-respiratory sleep disturbances in children with neurodisabilities: a systematic review.

Authors:  Catriona McDaid; Adwoa Parker; Arabella Scantlebury; Caroline Fairhurst; Vicky Dawson; Heather Elphick; Catherine Hewitt; Gemma Spiers; Megan Thomas; Bryony Beresford
Journal:  BMJ Open       Date:  2019-06-19       Impact factor: 2.692

5.  The Effects of Valerian on Sleep Quality, Depression, and State Anxiety in Hemodialysis Patients: A Randomized, Double-blind, Crossover Clinical Trial.

Authors:  Mohammad Reza Tammadon; Monir Nobahar; Zaynab Hydarinia-Naieni; Abbasali Ebrahimian; Raheb Ghorbani; Abbas Ali Vafaei
Journal:  Oman Med J       Date:  2021-03-31
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.