Literature DB >> 12120368

The biosynthesis of bisvertinolone: evidence for oxosorbicillinol as a direct precursor.

Naoki Abe1, Tadaharu Arakawa, Akira Hirota.   

Abstract

Biosynthetic incorporation of labeled sodium acetate into oxosorbicillinol in Trichoderma sp. USF-2690 suggests that oxosorbicillinol is derived from six acetate units, and subsequent bioconversion of the labeled oxosorbicillinol to bisvertinolone in the fermentation of the strain suggests that bisvertinolone is biosynthesized from oxosorbicillinol and sorbicillinol in a Michael-type reaction.

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Year:  2002        PMID： 12120368     DOI： 10.1039/b109505f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis†Electronic supplementary information (ESI) available: Containing all experimental details. See DOI: 10.1039/c3sc52911hClick here for additional data file.

Authors:  Ahmed Al Fahad; Amira Abood; Katja M Fisch; Anna Osipow; Jack Davison; Marija Avramović; Craig P Butts; Jörn Piel; Thomas J Simpson; Russell J Cox
Journal:  Chem Sci       Date:  2013-11-26       Impact factor: 9.825

2.  Mechanism and regulation of sorbicillin biosynthesis by Penicillium chrysogenum.

Authors:  Fernando Guzmán-Chávez; Oleksandr Salo; Yvonne Nygård; Peter P Lankhorst; Roel A L Bovenberg; Arnold J M Driessen
Journal:  Microb Biotechnol       Date:  2017-06-15       Impact factor: 5.813

3.  Sorbicillinoid-Based Metabolites from a Sponge-Derived Fungus Trichoderma saturnisporum.

Authors:  Junjun Meng; Wei Cheng; Hajar Heydari; Bin Wang; Kui Zhu; Belma Konuklugil; Wenhan Lin
Journal:  Mar Drugs       Date:  2018-07-04       Impact factor: 5.118

4.  In Vitro and In Vivo Antifungal Activity of Sorbicillinoids Produced by Trichoderma longibrachiatum.

Authors:  Men Thi Ngo; Minh Van Nguyen; Jae Woo Han; Myung Soo Park; Hun Kim; Gyung Ja Choi
Journal:  J Fungi (Basel)       Date:  2021-05-28

5.  In Vivo Study of the Sorbicillinoid Gene Cluster in Trichoderma reesei.

Authors:  Christian Derntl; Fernando Guzmán-Chávez; Thiago M Mello-de-Sousa; Hans-Jürgen Busse; Arnold J M Driessen; Robert L Mach; Astrid R Mach-Aigner
Journal:  Front Microbiol       Date:  2017-10-20       Impact factor: 6.064

6.  Constitutive hyperproduction of sorbicillinoids in Trichoderma reesei ZC121.

Authors:  Chengcheng Li; Fengming Lin; Wei Sun; Shaoxun Yuan; Zhihua Zhou; Fu-Gen Wu; Zhan Chen
Journal:  Biotechnol Biofuels       Date:  2018-10-25       Impact factor: 6.040
  6 in total

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