Literature DB >> 12120364

In vivo cleavage of a target RNA by copper kanamycin A. Direct observation by a fluorescence assay.

Chun-An Chen1, J A Cowan.   

Abstract

A novel fluorescence assay to monitor in vivo cleavage chemistry of RNA target sequences has been established and used to demonstrate the activity of copper aminoglycoside mediated degradation of RNA in bacterial cells.

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Year:  2002        PMID： 12120364     DOI： 10.1039/b108439a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Metallotherapeutics: novel strategies in drug design.

Authors:  Lalintip Hocharoen; James A Cowan
Journal:  Chemistry       Date:  2009-09-07       Impact factor: 5.236

2.  In Vivo Biochemistry: Single-Cell Dynamics of Cyclic Di-GMP in Escherichia coli in Response to Zinc Overload.

Authors:  Jongchan Yeo; Andrew B Dippel; Xin C Wang; Ming C Hammond
Journal:  Biochemistry       Date:  2017-11-02       Impact factor: 3.162

3.  Cellular activity of Rev response element RNA targeting metallopeptides.

Authors:  Yan Jin; J A Cowan
Journal:  J Biol Inorg Chem       Date:  2007-03-14       Impact factor: 3.862

Review 4.  The Supramolecular Self-Assembly of Aminoglycoside Antibiotics and their Applications.

Authors:  Ratan W Jadhav; Mohammad Al Kobaisi; Lathe A Jones; Ajayan Vinu; Sheshanath V Bhosale
Journal:  ChemistryOpen       Date:  2019-08-26       Impact factor: 2.911
  4 in total

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