Literature DB >> 12120152

Direct catalytic asymmetric aldol reactions of aldehydes.

Anders Bøgevig1, Nagaswamy Kumaragurubaran, Karl Anker Jørgensen.   

Abstract

The development of a direct catalytic enantioselective aldol reaction of aldehydes with activated carbonyl compounds catalyzed by chiral amines is presented and the potential demonstrated by the synthesis of optically active beta-hydroxycarboxylic acid derivatives.

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Year:  2002        PMID： 12120152     DOI： 10.1039/b200681b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  New mechanistic studies on the proline-catalyzed aldol reaction.

Authors:  Benjamin List; Linh Hoang; Harry J Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-08       Impact factor: 11.205

Review 2.  The direct catalytic asymmetric aldol reaction.

Authors:  Barry M Trost; Cheyenne S Brindle
Journal:  Chem Soc Rev       Date:  2010-02-17       Impact factor: 54.564

3.  Developing novel organocatalyzed aldol reactions for the enantioselective synthesis of biologically active molecules.

Authors:  Mayur Bhanushali; Cong-Gui Zhao
Journal:  Synthesis (Stuttg)       Date:  2011-06       Impact factor: 3.157

4.  Organocatalytic enantioselective synthesis of both diastereomers of alpha-hydroxyphosphinates.

Authors:  Sampak Samanta; Sandun Perera; Cong-Gui Zhao
Journal:  J Org Chem       Date:  2010-02-19       Impact factor: 4.354

5.  Asymmetric synthesis of 1H-pyrrol-3(2H)-ones from 2,3-diketoesters by combination of aldol condensation with benzilic acid rearrangement.

Authors:  Qiang Sha; Hadi Arman; Michael P Doyle
Journal:  Chem Commun (Camb)       Date:  2016-01-04       Impact factor: 6.222

6.  O-nitroso aldol synthesis: Catalytic enantioselective route to alpha-aminooxy carbonyl compounds via enamine intermediate.

Authors:  Norie Momiyama; Hiromi Torii; Susumu Saito; Hisashi Yamamoto
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-05       Impact factor: 11.205

7.  Enantioselective Iridium-Catalyzed Reductive Coupling of Dienes with Oxetanones and N-Acyl-Azetidinones Mediated by 2-Propanol.

Authors:  Cole C Meyer; Zachary J Dubey; Michael J Krische
Journal:  Angew Chem Int Ed Engl       Date:  2022-02-16       Impact factor: 15.336

8.  Synthesis, characterization, anti-inflammatory and in vitro antimicrobial activity of some novel alkyl/aryl substituted tertiary alcohols.

Authors:  Muhammad Baseer; Farzana Latif Ansari; Zaman Ashraf; Rafiuzzaman SaeedulHaq
Journal:  Molecules       Date:  2011-12-14       Impact factor: 4.411

9.  Differentiation between enamines and tautomerizable imines in the oxidation reaction with TEMPO.

Authors:  Xiaoming Jie; Yaping Shang; Zhe-Ning Chen; Xiaofeng Zhang; Wei Zhuang; Weiping Su
Journal:  Nat Commun       Date:  2018-11-27       Impact factor: 14.919

10.  A new charge-tagged proline-based organocatalyst for mechanistic studies using electrospray mass spectrometry.

Authors:  J Alexander Willms; Rita Beel; Martin L Schmidt; Christian Mundt; Marianne Engeser
Journal:  Beilstein J Org Chem       Date:  2014-08-28       Impact factor: 2.883
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