Literature DB >> 12120151

Engineered biosynthesis of novel spinosyns bearing altered deoxyhexose substituents.

Sabine Gaisser1, Christine J Martin, Barrie Wilkinson, Rose M Sheridan, Rachel E Lill, Alison J Weston, Sarah J Ready, Clive Waldron, Gary D Crouse, Peter F Leadlay, James Staunton.   

Abstract

Novel spinosyns have been prepared by biotransformation, using a genetically engineered strain of Saccharopolyspora erythraea, in which the beta-D-forosamine moiety in glycosidic linkage to the hydroxy group at C17 is replaced by alpha-L-mycarose.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12120151     DOI： 10.1039/b200536k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  Natural product derived insecticides: discovery and development of spinetoram.

Authors:  Ute Galm; Thomas C Sparks
Journal:  J Ind Microbiol Biotechnol       Date:  2015-11-18       Impact factor: 3.346

2.  Neural network-based QSAR and insecticide discovery: spinetoram.

Authors:  Thomas C Sparks; Gary D Crouse; James E Dripps; Peter Anzeveno; Jacek Martynow; Carl V Deamicis; James Gifford
Journal:  J Comput Aided Mol Des       Date:  2008-03-15       Impact factor: 3.686

3.  In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa.

Authors:  Lin Hong; Zongbao Zhao; Charles E Melançon; Hua Zhang; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2008-03-18       Impact factor: 15.419

4.  Butenyl-spinosyns, a natural example of genetic engineering of antibiotic biosynthetic genes.

Authors:  Donald R Hahn; Gary Gustafson; Clive Waldron; Brian Bullard; James D Jackson; Jon Mitchell
Journal:  J Ind Microbiol Biotechnol       Date:  2005-09-23       Impact factor: 3.346

Review 5.  Astonishing diversity of natural surfactants: 2. Polyether glycosidic ionophores and macrocyclic glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-03       Impact factor: 1.880

6.  New Sipanmycin Analogues Generated by Combinatorial Biosynthesis and Mutasynthesis Approaches Relying on the Substrate Flexibility of Key Enzymes in the Biosynthetic Pathway.

Authors:  Mónica G Malmierca; Ignacio Pérez-Victoria; Jesús Martín; Fernando Reyes; Carmen Méndez; José A Salas; Carlos Olano
Journal:  Appl Environ Microbiol       Date:  2020-01-21       Impact factor: 4.792

Review 7.  Microbial drug discovery: 80 years of progress.

Authors:  Arnold L Demain; Sergio Sanchez
Journal:  J Antibiot (Tokyo)       Date:  2009-01-09       Impact factor: 2.649
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.