Literature DB >> 12119745

New treatments for COPD.

Peter J Barnes1.   

Abstract

COPD is one of the most common diseases in the world, and there is a global increase in prevalence, but there are no drugs available at present that halt the relentless progression of this disease. However, a better understanding of the cellular and molecular mechanisms that are involved in the underlying inflammatory and destructive processes has revealed several new targets for which drugs are now in development, and the prospects for finding new treatments are good.

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Year:  2002        PMID: 12119745     DOI: 10.1038/nrd820

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  25 in total

Review 1.  Innate immune responses and chronic obstructive pulmonary disease: "Terminator" or "Terminator 2"?

Authors:  Robert P Schleimer
Journal:  Proc Am Thorac Soc       Date:  2005

2.  Determining the functional role of TRPC channels in primary cells.

Authors:  Su Li; Martin Gosling; Chris Poll
Journal:  Pflugers Arch       Date:  2005-08-03       Impact factor: 3.657

3.  Activity monitoring and energy expenditure in COPD patients: a validation study.

Authors:  Sanjay A Patel; Roberto P Benzo; William A Slivka; Frank C Sciurba
Journal:  COPD       Date:  2007-06       Impact factor: 2.409

Review 4.  Chronic obstructive pulmonary disease * 12: New treatments for COPD.

Authors:  P J Barnes
Journal:  Thorax       Date:  2003-09       Impact factor: 9.139

5.  Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice.

Authors:  Megan Podowski; Carla Calvi; Shana Metzger; Kaori Misono; Hataya Poonyagariyagorn; Armando Lopez-Mercado; Therese Ku; Thomas Lauer; Sharon McGrath-Morrow; Alan Berger; Christopher Cheadle; Rubin Tuder; Harry C Dietz; Wayne Mitzner; Robert Wise; Enid Neptune
Journal:  J Clin Invest       Date:  2011-12-19       Impact factor: 14.808

6.  ATF3 and extracellular matrix-related genes associated with the process of chronic obstructive pulmonary.

Authors:  Jia Ye; Li Wen; De-Ling Liu; Guo-xiang Lai
Journal:  Lung       Date:  2014-08-14       Impact factor: 2.584

7.  TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells.

Authors:  Mark E Johansen; Christopher A Reilly; Garold S Yost
Journal:  Toxicol Sci       Date:  2005-08-24       Impact factor: 4.849

8.  Knowledge and attitudes of family physicians coming to COPD continuing medical education.

Authors:  Barbara P Yawn; Peter C Wollan
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2008

9.  The influence of free 3-nitrotyrosine and saliva on the quantitative analysis of protein-bound 3-nitrotyrosine in sputum.

Authors:  Kazuhito Ueshima; Yoshiaki Minakata; Hisatoshi Sugiura; Satoru Yanagisawa; Tomohiro Ichikawa; Keiichirou Akamatsu; Tsunahiko Hirano; Masanori Nakanishi; Kazuto Matsunaga; Toshiyuki Yamagata; Masakazu Ichinose
Journal:  Anal Chem Insights       Date:  2007-02-14

10.  Superoxide release from contracting skeletal muscle in pulmonary TNF-α overexpression mice.

Authors:  Li Zuo; Allison H Hallman; William J Roberts; Peter D Wagner; Michael C Hogan
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-11-06       Impact factor: 3.619

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