Literature DB >> 12119320

Is there a schizophasia? A study applying the single case approach to formal thought disorder in schizophrenia.

T M Oh1, R A McCarthy, P J McKenna.   

Abstract

It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also analysed using Brief Syntactic Analysis. Poor performance on the aphasia test battery was found to be associated with general intellectual impairment but not with formal thought disorder. Naming was preserved in both groups. Patients with formal thought disorder, but not those without, produced semantic errors in their spontaneous speech, and these were unrelated to general intellectual status. The disorder of language in formal thought disorder thus appears to be one of expressive semantic abnormality, which, however, spares naming. Further analysis of two intellectually preserved patients suggested that formal thought disorder may be associated with an additional difficulty in constructing an appropriate model for generating one's own speech.

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Year:  2002        PMID: 12119320     DOI: 10.1093/neucas/8.3.233

Source DB:  PubMed          Journal:  Neurocase        ISSN: 1355-4794            Impact factor:   0.881


  12 in total

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5.  The Genetic Basis of Thought Disorder and Language and Communication Disturbances in Schizophrenia.

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6.  The linguistics of schizophrenia: thought disturbance as language pathology across positive symptoms.

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7.  Deictic and Propositional Meaning-New Perspectives on Language in Schizophrenia.

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9.  The language profile of formal thought disorder.

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10.  Metabolic changes in schizophrenia and human brain evolution.

Authors:  Philipp Khaitovich; Helen E Lockstone; Matthew T Wayland; Tsz M Tsang; Samantha D Jayatilaka; Arfu J Guo; Jie Zhou; Mehmet Somel; Laura W Harris; Elaine Holmes; Svante Pääbo; Sabine Bahn
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