Literature DB >> 12119101

Genomic analysis of the murine odorant receptor MOR28 cluster: a possible role of gene conversion in maintaining the olfactory map.

Fumikiyo Nagawa1, Sei-ichi Yoshihara, Akio Tsuboi, Shou Serizawa, Keita Itoh, Hitoshi Sakano.   

Abstract

Genomic analysis was performed for the murine odorant receptor (OR) genes. The MOR28 cluster on chromosome 14 was extensively studied. It contains six OR genes, MOR28, 10, 83, 29A, 29B and 30. The human homolog of this cluster is located on the human chromosome 14, and contains five OR genes, HOR28/10, 83, 29A, 29B and 30. Sequence comparison of these OR gene paralogs and orthologs suggests that the coding homologies are accounted for not only by recent gene duplication, but also by gene conversion among the coding sequences within the cluster. A possible role of gene conversion in the olfactory system is discussed in the context of the olfactory map.

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Year:  2002        PMID： 12119101     DOI： 10.1016/s0378-1119(02)00670-4

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  8 in total

1.  The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla.

Authors:  Andrey A Perelygin; Andrey A Zharkikh; Svetlana V Scherbik; Margo A Brinton
Journal:  J Mol Evol       Date:  2006-10-05       Impact factor: 2.395

2.  Chromosomal location-dependent nonstochastic onset of odor receptor expression.

Authors:  Diego J Rodriguez-Gil; Helen B Treloar; Xiaohong Zhang; Alexandra M Miller; Aimee Two; Carrie Iwema; Stuart J Firestein; Charles A Greer
Journal:  J Neurosci       Date:  2010-07-28       Impact factor: 6.167

3.  Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis.

Authors:  Hirofumi Nishizumi; Kouhei Kumasaka; Nobuko Inoue; Ai Nakashima; Hitoshi Sakano
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-05       Impact factor: 11.205

4.  Uncoupling stimulus specificity and glomerular position in the mouse olfactory system.

Authors:  Jingji Zhang; Guangzhe Huang; Adam Dewan; Paul Feinstein; Thomas Bozza
Journal:  Mol Cell Neurosci       Date:  2012-08-21       Impact factor: 4.314

5.  Bioinformatics Discovery of Putative Enhancers within Mouse Odorant Receptor Gene Clusters.

Authors:  James E Farber; Robert P Lane
Journal:  Chem Senses       Date:  2019-10-26       Impact factor: 3.160

6.  Functional interrogation of an odorant receptor locus reveals multiple axes of transcriptional regulation.

Authors:  Alexander Fleischmann; Ishmail Abdus-Saboor; Atef Sayed; Benjamin Shykind
Journal:  PLoS Biol       Date:  2013-05-21       Impact factor: 8.029

7.  Setting limits: maintaining order in a large gene family.

Authors:  Ishmail Abdus-Saboor; Alexander Fleischmann; Benjamin Shykind
Journal:  Transcription       Date:  2014

8.  Expansion and Accelerated Evolution of 9-Exon Odorant Receptors in Polistes Paper Wasps.

Authors:  Andrew W Legan; Christopher M Jernigan; Sara E Miller; Matthieu F Fuchs; Michael J Sheehan
Journal:  Mol Biol Evol       Date:  2021-08-23       Impact factor: 16.240
  8 in total

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