| Literature DB >> 12118726 |
A C M Bonné1, M G C W den Bieman, G F Gillissen, L F M van Zutphen, H A van Lith.
Abstract
A genetic linkage map consisting of 258 polymorphic loci has been constructed on the basis of an F2 intercross between the BC/CpbU and LEW/OlaHsd inbred rat strains. When compared to previously published maps a discrepancy was found for rat chromosome 7. The map spans a sex-averaged genetic length of 1790 cM and has an average marker spacing of 7.7 cM. It was estimated that this genetic map is linked to about 90% of the DNA in the rat genome. Because LEW/OlaHsd and BC/CpbU strains differ for dietary cholesterol susceptibility and hepatic copper content, the map is considered to be a valuable tool for studying the genetic background of these complex traits.Entities:
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Year: 2002 PMID： 12118726
Source DB: PubMed Journal: Folia Biol (Praha) ISSN： 0015-5500 Impact factor: 0.906