Literature DB >> 12118505

Cytotoxic macrocyclic trichothecenes from the mycelia of Calcarisporium arbuscula Preuss.

Neng-Jiang Yu1, Shun-Xing Guo, Hai-Yan Lu.   

Abstract

A new cytotoxic macrocyclic trichothecene calcarisporin B1 (1), and two known compounds roridin H (2) and roridin J (3) were isolated from the cultured mycelia of Calcarisporium arbuscula Preuss. The structure of 1 was determined to be 8alpha-acetoxy roridin H on the basis of spectral data. The cytotoxic activities of 1-3 were evaluated in vitro.

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Year:  2002        PMID: 12118505     DOI: 10.1080/10286020290011387

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  5 in total

1.  Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products.

Authors:  Xu-Ming Mao; Wei Xu; Dehai Li; Wen-Bing Yin; Yit-Heng Chooi; Yong-Quan Li; Yi Tang; Youcai Hu
Journal:  Angew Chem Int Ed Engl       Date:  2015-05-27       Impact factor: 15.336

2.  Dereplication of macrocyclic trichothecenes from extracts of filamentous fungi through UV and NMR profiles.

Authors:  Arlene A Sy-Cordero; Tyler N Graf; Mansukh C Wani; David J Kroll; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Antibiot (Tokyo)       Date:  2010-07-21       Impact factor: 2.649

3.  Production of Calcaride A by Calcarisporium sp. in Shaken Flasks and Stirred Bioreactors.

Authors:  Anu Tamminen; Yanming Wang; Marilyn G Wiebe
Journal:  Mar Drugs       Date:  2015-06-24       Impact factor: 5.118

Review 4.  Recent Advances on Macrocyclic Trichothecenes, Their Bioactivities and Biosynthetic Pathway.

Authors:  Muzi Zhu; Youfei Cen; Wei Ye; Saini Li; Weimin Zhang
Journal:  Toxins (Basel)       Date:  2020-06-23       Impact factor: 4.546

5.  Growth of marine fungi on polymeric substrates.

Authors:  Yanming Wang; Dorothee Barth; Anu Tamminen; Marilyn G Wiebe
Journal:  BMC Biotechnol       Date:  2016-01-16       Impact factor: 2.563

  5 in total

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