Literature DB >> 12116832

Clinical results and thoughts on sensory nerve repair by autologous vein graft in emergency hand reconstruction.

G Risitano1, G Cavallaro, T Merrino, S Coppolino, F Ruggeri.   

Abstract

Lesions of the digital and other sensory nerves in the hand are common. Based on experimental studies on vein graft as a support for peripheral nerve regeneration, the Authors have been using a simple vein graft to bridge sensory nerve gaps when treating acute hand injuries. This is a retrospective study on the results of 22 sensory nerves repaired using vein grafts in cases in which primary suture was not feasible, in emergency hand reconstruction. Patients were informed that a secondary nerve graft could possibly be necessary in the future. Patients were reviewed by two independent observers at least one year after repair and evaluated using the Highest scale as modified by MacKinnon & Dellon. Evaluation chart included influence of repair on rehabilitation program and presence of painful neuromas and scars as well as patient satisfaction. Results were classified according to Sakellarides and 20/22 were classified as very good or good. Cases classified as poor were satisfied and no secondary nerve grafting has been carried out. Rehabilitation of the associated lesions (tendon lacerations or bone and soft tissue damage) was not influenced by the nerve repair and no painful neuroma was reported in the series. In conclusion, since the literature shows unsatisfactory results in repair of digital nerves with nerve grafts, since it's been demonstrated that an unrepaired sensory nerve leads to painful scar and painful neuroma and since we are reluctant to use nerve grafts in emergency procedures, we recommend this simple method because it is easy, low-cost and effective.

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Mesh:

Year:  2002        PMID: 12116832     DOI: 10.1016/s1297-3203(02)00109-9

Source DB:  PubMed          Journal:  Chir Main        ISSN: 1297-3203


  8 in total

Review 1.  Biomaterials for the development of peripheral nerve guidance conduits.

Authors:  Alexander R Nectow; Kacey G Marra; David L Kaplan
Journal:  Tissue Eng Part B Rev       Date:  2011-09-23       Impact factor: 6.389

Review 2.  [Nerve injuries and posttraumatic therapy].

Authors:  C Radtke; P M Vogt
Journal:  Unfallchirurg       Date:  2014-06       Impact factor: 1.000

3.  Closing the Gap: Bridging Peripheral Sensory Nerve Defects with a Chitosan-Based Conduit a Randomized Prospective Clinical Trial.

Authors:  Arne Böcker; Martin Aman; Ulrich Kneser; Leila Harhaus; Frank Siemers; Felix Stang
Journal:  J Pers Med       Date:  2022-05-30

4.  Inside-out autologous vein grafts fail to restore erectile function in a rat model of cavernous nerve crush injury after nerve-sparing prostatectomy.

Authors:  T Bessede; D Moszkowicz; B Alsaid; M Zaitouna; D Diallo; F Peschaud; G Benoit; S Droupy
Journal:  Int J Impot Res       Date:  2014-07-31       Impact factor: 2.896

5.  Digital nerve injuries: a review of predictors of sensory recovery after microsurgical digital nerve repair.

Authors:  Joline F Mermans; Bas B G M Franssen; Jan Serroyen; Rene R W J Van der Hulst
Journal:  Hand (N Y)       Date:  2012-06-28

6.  Adult-brain-derived neural stem cells grafting into a vein bridge increases postlesional recovery and regeneration in a peripheral nerve of adult pig.

Authors:  Olivier Liard; Stéphanie Segura; Emmanuel Sagui; André Nau; Aurélie Pascual; Melissa Cambon; Jean-Luc Darlix; Thierry Fusai; Emmanuel Moyse
Journal:  Stem Cells Int       Date:  2012-02-02       Impact factor: 5.443

7.  Scaffoldless tissue-engineered nerve conduit promotes peripheral nerve regeneration and functional recovery after tibial nerve injury in rats.

Authors:  Aaron M Adams; Keith W VanDusen; Tatiana Y Kostrominova; Jacob P Mertens; Lisa M Larkin
Journal:  Neural Regen Res       Date:  2017-09       Impact factor: 6.058

8.  Sensory recovery outcome after digital nerve repair in relation to different reconstructive techniques: meta-analysis and systematic review.

Authors:  Felix J Paprottka; Petra Wolf; Yves Harder; Yasmin Kern; Philipp M Paprottka; Hans-Günther Machens; Jörn A Lohmeyer
Journal:  Plast Surg Int       Date:  2013-07-30
  8 in total

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