Literature DB >> 12116037

Transforming growth factor-beta enhances human T-cell leukemia virus type I infection.

Masako Moriuchi1, Hiroyuki Moriuchi.   

Abstract

Human T-cell leukemia virus type I (HTLV-I), the causative agent of adult T-cell leukemia/lymphoma, is transmitted vertically by breast milk and sexually by semen. The transforming growth factor-beta (TGF-beta), a pleiotropic cytokine that is abundant in breast milk and semen, facilitates replication of HTLV-I in lymphocytes derived from asymptomatic HTLV-I carriers and transmission to cord blood lymphocytes in vitro. Transient expression assays revealed that TGF-beta can transactivate HTLV-I long terminal repeat promoter. These results suggest that TGF-beta may play a role in replication and transmission of HTLV-I. Copyright 2002 Wiley-Liss, Inc.

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Year:  2002        PMID： 12116037     DOI： 10.1002/jmv.10074

Source DB:  PubMed          Journal:  J Med Virol        ISSN： 0146-6615            Impact factor:   2.327


  11 in total

1.  Transforming growth factor beta enhances respiratory syncytial virus replication and tumor necrosis factor alpha induction in human epithelial cells.

Authors:  Kelly L McCann; Farhad Imani
Journal:  J Virol       Date:  2007-01-03       Impact factor: 5.103

2.  Induction of lactoferrin gene expression in myeloid or mammary gland cells by human T-cell leukemia virus type 1 (HTLV-1) tax: implications for milk-borne transmission of HTLV-1.

Authors:  Masako Moriuchi; Hiroyuki Moriuchi
Journal:  J Virol       Date:  2006-07       Impact factor: 5.103

3.  Route of primary HTLV-1 infection regulates HTLV-1 distribution in reservoir organs of infected mice.

Authors:  Masakazu Tanaka; Takayuki Nitta; Binlian Sun; Jun-Ichi Fujisawa; Masanao Miwa
Journal:  Exp Ther Med       Date:  2010-12-02       Impact factor: 2.447

4.  Seminal fluid enhances replication of human T-cell leukemia virus type 1: implications for sexual transmission.

Authors:  Masako Moriuchi; Hiroyuki Moriuchi
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

Review 5.  Current concepts regarding the HTLV-1 receptor complex.

Authors:  David Ghez; Yves Lepelletier; Kathryn S Jones; Claudine Pique; Olivier Hermine
Journal:  Retrovirology       Date:  2010-11-29       Impact factor: 4.602

6.  Cellular Factors Involved in HTLV-1 Entry and Pathogenicit.

Authors:  Hiroo Hoshino
Journal:  Front Microbiol       Date:  2012-06-21       Impact factor: 5.640

Review 7.  The HTLV-1 Tax interactome.

Authors:  Mathieu Boxus; Jean-Claude Twizere; Sébastien Legros; Jean-François Dewulf; Richard Kettmann; Luc Willems
Journal:  Retrovirology       Date:  2008-08-14       Impact factor: 4.602

Review 8.  A Nationwide Antenatal Human T-Cell Leukemia Virus Type-1 Antibody Screening in Japan.

Authors:  Kazuo Itabashi; Tokuo Miyazawa; Akihiko Sekizawa; Akifumi Tokita; Shigeru Saito; Hiroyuki Moriuchi; Yasuhito Nerome; Kaoru Uchimaru; Toshiki Watanabe
Journal:  Front Microbiol       Date:  2020-04-09       Impact factor: 5.640

Review 9.  Molecular Studies of HTLV-1 Replication: An Update.

Authors:  Jessica L Martin; José O Maldonado; Joachim D Mueller; Wei Zhang; Louis M Mansky
Journal:  Viruses       Date:  2016-01-27       Impact factor: 5.048

10.  The Binary Classification Of Chronic Diseases.

Authors:  Zeev Elkoshi
Journal:  J Inflamm Res       Date:  2019-12-16
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