Literature DB >> 12114633

Endothelial Regulation of Vascular Repair: Role of bFGF in Paracrine Pathways.

Avrum I. Gotlieb.   

Abstract

Vascular repair following injury is mediated by both endothelial and smooth muscle cells often through paracrine pathways. Basic fibroblast growth factor (bFGF) is present at sites of vascular injury. The role of bFGF in regulating reendothelialization through an effect on centrosome redistribution in cell migration is discussed. The role of bFGF in neointimal formation, especially as it relates to smooth muscle cell proliferation, is reviewed. It is concluded that bFGF appears to be an important agent regulating the early responses of the artery wall to injury.

Entities:  

Year:  1997        PMID： 12114633     DOI： 10.1007/bf02739941

Source DB:  PubMed          Journal:  Endocr Pathol        ISSN： 1046-3976            Impact factor:   3.943


  13 in total

1.  Centrosomes, microtubules, and microfilaments in the reendothelialization and remodeling of double-sided in vitro wounds.

Authors:  D S Ettenson; A I Gotlieb
Journal:  Lab Invest       Date:  1992-06       Impact factor: 5.662

2.  Decreased blood flow rate disrupts endothelial repair in vivo.

Authors:  S Vyalov; B L Langille; A I Gotlieb
Journal:  Am J Pathol       Date:  1996-12       Impact factor: 4.307

3.  Endothelial stimulation of intimal cell proliferation in a porcine aortic organ culture.

Authors:  E W Koo; A I Gotlieb
Journal:  Am J Pathol       Date:  1989-03       Impact factor: 4.307

4.  Transition of aortic endothelial cells from resting to migrating cells is associated with three sequential patterns of microfilament organization.

Authors:  T Y Lee; A Rosenthal; A I Gotlieb
Journal:  J Vasc Res       Date:  1996 Jan-Feb       Impact factor: 1.934

5.  Monocyte adhesion and changes in endothelial cell number, morphology, and F-actin distribution elicited by low shear stress in vivo.

Authors:  P L Walpola; A I Gotlieb; B L Langille
Journal:  Am J Pathol       Date:  1993-05       Impact factor: 4.307

6.  In vitro large-wound re-endothelialization. Inhibition of centrosome redistribution by transient inhibition of transcription after wounding prevents rapid repair.

Authors:  D S Ettenson; A I Gotlieb
Journal:  Arterioscler Thromb       Date:  1993-09

Review 7.  The pathogenesis of atherosclerosis: a perspective for the 1990s.

Authors:  R Ross
Journal:  Nature       Date:  1993-04-29       Impact factor: 49.962

8.  Proliferating arterial smooth muscle cells after balloon injury express TNF-alpha but not interleukin-1 or basic fibroblast growth factor.

Authors:  H Tanaka; G Sukhova; D Schwartz; P Libby
Journal:  Arterioscler Thromb Vasc Biol       Date:  1996-01       Impact factor: 8.311

9.  Basic fibroblast growth factor is a signal for the initiation of centrosome redistribution to the front of migrating endothelial cells at the edge of an in vitro wound.

Authors:  D S Ettenson; A I Gotlieb
Journal:  Arterioscler Thromb Vasc Biol       Date:  1995-04       Impact factor: 8.311

10.  The reorganization of microfilaments, centrosomes, and microtubules during in vitro small wound reendothelialization.

Authors:  M K Wong; A I Gotlieb
Journal:  J Cell Biol       Date:  1988-11       Impact factor: 10.539
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.