Literature DB >> 12113818

Inhibition of ADP-triggered blood platelet aggregation by diadenosine polyphosphate analogues.

Bogdan Walkowiak1, Janina Baraniak, Czeslaw S Cierniewski, Wojciech Stec.   

Abstract

The synthesis and biological evaluation of new diadenosine polyphosphate analogues on blood platelet aggregation are reported. The most active are compounds with a sulfur atom replacing one or both non-bridging oxygens at phosphorus bound to adenosyl residues and hydroxymethyl groups of bis(hydroxymethyl)phosphinic acid.

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Year:  2002        PMID: 12113818     DOI: 10.1016/s0960-894x(02)00318-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  P1,P2-diimidazolyl derivatives of pyrophosphate and bis-phosphonates--synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs.

Authors:  Ivan B Yanachkov; Edward J Dix; Milka I Yanachkova; George E Wright
Journal:  Org Biomol Chem       Date:  2010-11-17       Impact factor: 3.876

Review 2.  Ca2+ signalling in brain synaptosomes activated by dinucleotides.

Authors:  M T Miras-Portugal; J Pintor; J Gualix
Journal:  J Membr Biol       Date:  2003-07-01       Impact factor: 1.843

  2 in total

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