Literature DB >> 12113190

Taking ACE inhibitors during pregnancy. Is it safe?

Savithiri Ratnapalan1, Gideon Koren.   

Abstract

QUESTION: A pregnant patient is taking enalapril for primary hypertension. How safe are angiotension-converting enzyme inhibitors (ACEI) during pregnancy? ANSWER: Evidence of whether ACEIs cause problems during the first trimester of pregnancy is reassuring. There is evidence that they cause severe renal and other problems during the second and third trimesters, however. These drugs should be avoided during pregnancy.

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Year:  2002        PMID： 12113190      PMCID： PMC2214066     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  14 in total

1.  Low-dose, short-acting, angiotensin-converting enzyme inhibitors as rescue therapy in pregnancy.

Authors:  T R Easterling; D B Carr; C Davis; C Diederichs; D A Brateng; B Schmucker
Journal:  Obstet Gynecol       Date:  2000-12       Impact factor: 7.661

2.  Low-dose, short-acting, angiotensin-converting enzyme inhibitors as rescue therapy in pregnancy.

Authors:  P G Pryde; M Barr
Journal:  Obstet Gynecol       Date:  2001-05       Impact factor: 7.661

3.  Angiotensin-II-receptor inhibitors in pregnancy.

Authors:  N A Chung; G Y Lip; M Beevers; D G Beevers
Journal:  Lancet       Date:  2001-05-19       Impact factor: 79.321

Review 4.  Angiotensin converting enzyme inhibitors in pregnancy.

Authors:  J M Mastrobattista
Journal:  Semin Perinatol       Date:  1997-04       Impact factor: 3.300

Review 5.  Assessing the teratogenic potential of angiotensin-converting enzyme inhibitors in pregnancy.

Authors:  R F Burrows; E A Burrows
Journal:  Aust N Z J Obstet Gynaecol       Date:  1998-08       Impact factor: 2.100

6.  Enalapril for pregnancy-induced hypertension: acute renal failure in a neonate.

Authors:  G Schubiger; G Flury; J Nussberger
Journal:  Ann Intern Med       Date:  1988-02       Impact factor: 25.391

7.  Angiotensin-converting enzyme inhibitors during pregnancy: a survey of 22 patients given captopril and nine given enalapril.

Authors:  C Kreft-Jais; P F Plouin; C Tchobroutsky; M J Boutroy
Journal:  Br J Obstet Gynaecol       Date:  1988-04

8.  Placental passage of angiotensin-converting enzyme inhibitors.

Authors:  K Reisenberger; C Egarter; B Sternberger; P Eckenberger; E Eberle; E R Weissenbacher
Journal:  Am J Obstet Gynecol       Date:  1996-05       Impact factor: 8.661

9.  Neonatal anuria with maternal angiotensin-converting enzyme inhibition.

Authors:  F W Rosa; L A Bosco; C F Graham; J B Milstien; M Dreis; J Creamer
Journal:  Obstet Gynecol       Date:  1989-09       Impact factor: 7.661

Review 10.  Teratogen update: angiotensin-converting enzyme inhibitors.

Authors:  M Barr
Journal:  Teratology       Date:  1994-12
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  8 in total

1.  Hypertension: ACE inhibitor use in pregnancy--setting the record straight.

Authors:  Gideon Koren
Journal:  Nat Rev Cardiol       Date:  2011-11-22       Impact factor: 32.419

2.  Taking angiotensin-converting enzyme inhibitors during pregnancy: is it safe?

Authors:  Almundher Al-Maawali; Asnat Walfisch; Gideon Koren
Journal:  Can Fam Physician       Date:  2012-01       Impact factor: 3.275

3.  Prescription of antihypertensive medications during pregnancy in the UK.

Authors:  Lucia Cea Soriano; Brian T Bateman; Luis A García Rodríguez; Sonia Hernández-Díaz
Journal:  Pharmacoepidemiol Drug Saf       Date:  2014-05-02       Impact factor: 2.890

4.  ACE inhibitors on ACE1, ACE2, and TMPRSS2 expression and spheroid attachment on human endometrial Ishikawa cells.

Authors:  Sudini R Fernando; Xian Chen; Kiu-Wai Cheng; Benancy Pc Wong; Shiwen Qi; Luhan Jiang; Suranga P Kodithuwakku; Ernest Hy Ng; William Sb Yeung; Kai-Fai Lee
Journal:  Reprod Biol       Date:  2022-06-07       Impact factor: 2.089

5.  Nursing Across the Lifespan: Implications of Lifecourse Theory for Nursing Research.

Authors:  Randi A Bates; Lisa M Blair; Emma C Schlegel; Colleen M McGovern; Marliese Dion Nist; Stephanie Sealschott; Kimberly Arcoleo
Journal:  J Pediatr Health Care       Date:  2017-09-07       Impact factor: 1.812

6.  Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: a retrospective cohort study.

Authors:  De-Kun Li; Chunmei Yang; Susan Andrade; Venessa Tavares; Jeannette R Ferber
Journal:  BMJ       Date:  2011-10-18

7.  Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit.

Authors:  Lawrence C Ku; Kanecia Zimmerman; Daniel K Benjamin; Reese H Clark; Christoph P Hornik; P Brian Smith
Journal:  Pediatr Cardiol       Date:  2016-11-08       Impact factor: 1.838

Review 8.  Antihypertensive agents: a long way to safe drug prescribing in children.

Authors:  Nida Siddiqi; Ibrahim F Shatat
Journal:  Pediatr Nephrol       Date:  2019-11-01       Impact factor: 3.651
  8 in total

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