C Ann McDonald1, David G Bruce, David J Smith. 1. Department of Postgraduate Psychiatry Training, Graylands Hospital, Perth, Australia. ann.mcdonald@health .wa.gov.au
Abstract
BACKGROUND: Clinical case of primary hyperparathyroidism in an 89 year old woman causing profound neuropsychiatric symptoms associated with relatively mild increases in serum calcium levels. OBJECTIVES: To demonstrate that lowering of serum calcium levels by medical treatment (biphosphonate), provided a scientific basis from which to treat a very elderly woman with neuropsychiatric symptoms with definitive surgery. METHOD: Case report. RESULTS: The use of biphosphonate therapy led to marked but temporary improvements in her mental state. CONCLUSION: A trial of reducing serum calcium levels with biphosphonate appears to be indicated in elderly patients with mild primary hyperparathyroidism and neuropsychiatric disorders. Copyright 2002 John Wiley & Sons, Ltd.
BACKGROUND: Clinical case of primary hyperparathyroidism in an 89 year old woman causing profound neuropsychiatric symptoms associated with relatively mild increases in serum calcium levels. OBJECTIVES: To demonstrate that lowering of serum calcium levels by medical treatment (biphosphonate), provided a scientific basis from which to treat a very elderly woman with neuropsychiatric symptoms with definitive surgery. METHOD: Case report. RESULTS: The use of biphosphonate therapy led to marked but temporary improvements in her mental state. CONCLUSION: A trial of reducing serum calcium levels with biphosphonate appears to be indicated in elderly patients with mild primary hyperparathyroidism and neuropsychiatric disorders. Copyright 2002 John Wiley & Sons, Ltd.
Authors: Josiana de Oliveira Martins Duarte; Paula Maria Lobato Pestana Pereira; João Nuno Gamito Lopes; Ana Teresa Loução Goes; David Campoamor Durán; Ana Sofia Gonçalves Nunes Sobral; Henrique José Barrelas Rita; José António de Sousa E Costa Journal: Clin Case Rep Date: 2019-11-24