Literature DB >> 12111826

Oligodendrocytes as providers of growth factors.

Yangzhou Du1, Cheryl F Dreyfus.   

Abstract

Glial cells recently are being appreciated as supporters of brain neurons. This review addresses their role as growth factor providers. While the function of astrocytes in this capacity is known, new data indicate that oligodendrocytes, the myelinating cells of the brain, exhibit similar abilities. Oligodendrocytes provide trophic signals to nearby neurons and synthesize defined growth factors. Expression of growth factors is influenced by neural signals. The review summarizes these roles and their implications in brain function. Copyright 2002 Wiley-Liss, Inc.

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Year:  2002        PMID： 12111826     DOI： 10.1002/jnr.10245

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN： 0360-4012            Impact factor:   4.164


  79 in total

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