Analysis and implications of aircraft disinsectants.

Aircraft disinsection is required by various countries. In-flight spraying with a 2% phenothrin aerosol exposes passengers and crew directly. Residual spaying uses a permethrin emulsions in the absence of passengers and crew and results in dermal and oral exposures. Exposed passengers and crew often complain of, skin rashes, respiratory problems, tingling and numbness in fingertips and lips and burning eyes. A number of formulations were analyzed for their constituents using GLC-Mass. spec. Volatile organic compounds (VOCs) were found in all aerosol preparations including, ethyl benzene and xylene isomers along with phenothrin. Residual sprays contained, cis-, and trans-, permethrins, palmidrol, and occasionally naphthalene. Headspace analysis found methylene chloride and hexene derivatives but not the active ingredients. The known synergistic effects between organophosphates and pyrethrins, based on carboxyesterases inhibition, can be expected in the presence of Tricresylphosphates (TCPs), constituents found in jet engine oils and in some hydraulic fluids. During oil seal failure, the presence of TCP in the ventilation air could explain the increased sensitivity of some crew members and passengers to disinsectants.