Literature DB >> 1210681

[The relationship between the formation of trace reactions and the functional state of rats of different genetic lines].

Iu S Dmitriev.   

Abstract

The level of excitability of the nervous system was enhanced in rats of the Krushinsky--Molodkina (K--M) and Wistar (W) lines by means of dynamic and static physical loads and injections of different doses of al-amphetamine. It was shown that a higher level of excitability of the central nervous system produced in both lines of rats improved memory and increased the rate of formation of a conditioned active aboidance reflex (CAAR). A greater physical load or dose of the stimulant drug in the K-M line of rats resulted in a decrease of all parameters characterizing CAAR, while in the other line they rose in progression. The data obtained are believed to be related to a different genetically conditioned initial level of excitability in the indicated lines of rats--a higher one in the K--M line animals as compared with the W line rats, which determines a different norm of the nervous system responsiveness in the indicated groups of animals.

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Year:  1975        PMID: 1210681

Source DB:  PubMed          Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova        ISSN: 0044-4677            Impact factor:   0.437


  1 in total

1.  Role of genetic factors in the formation of human trace responses.

Authors:  V F Mikheev
Journal:  Neurosci Behav Physiol       Date:  1981 Mar-Apr
  1 in total

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