| Literature DB >> 12106792 |
Abstract
The glycosylphosphatidylinositol (GPI) anchors of Plasmodium falciparum are thought to be etiologic agents of malaria based on their ability to induce proinflammatory cytokine production by macrophages and cause symptoms that resemble severe malaria illness in animals. This review summarizes the published information on the structures of P. falciparum GPIs, structure-activity relationship, and anti-GPI antibodies in the host.Entities:
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Year: 2002 PMID: 12106792 DOI: 10.1016/s1286-4579(02)01619-2
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700