| Literature DB >> 12101034 |
Marina E Trofimova-Griffin1, Mont R Juchau.
Abstract
Expression levels of cytochrome CYP26B1, which is involved in the specific all-trans-RA inactivation, were evaluated in human cephalic tissues at gestational days 57-110 and exhibited values approximately 10-fold higher than later gestational days 112-224 and adult tissues. CYP26B1 mRNA levels in the adult cerebellum were approximately 2-fold higher than in the adult whole brain tissue. Considered together, these data suggest a unique role for CYP26B1 during human brain development.Entities:
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Year: 2002 PMID: 12101034 DOI: 10.1016/s0165-3806(02)00305-x
Source DB: PubMed Journal: Brain Res Dev Brain Res ISSN: 0165-3806