| Literature DB >> 12100139 |
Jun Ooi1, Tohru Iseki, Satoshi Takahashi, Akira Tomonari, Hitomi Nagayama, Koji Ishii, Kiyoshi Ito, Hiroyuki Sato, Tsutomu Takahashi, Motohiro Shindo, Rieko Sekine, Nobuhiro Ohno, Kaoru Uchimaru, Fumitaka Nagamura, Naoki Shirafuji, Arinobu Tojo, Kenzaburo Tani, Shigetaka Asano.
Abstract
We performed a clinical comparison of unrelated cord blood transplantation (UCBT) and unrelated bone marrow transplantation in adult acute leukaemia patients in complete remission (CR) who received the same conditioning regimen, graft-versus-host disease (GvHD) prophylaxis and supportive treatment. The incidence of acute GvHD was almost the same between the two groups, but the haematopoietic recovery was delayed and the incidence of chronic GvHD was higher in the UCBT group. The probability of 2 year disease-free survival was similar between the two groups. These results suggest that adult acute leukaemia patients in CR without a suitable donor should be considered as candidates for UCBT.Entities:
Mesh：
Year: 2002 PMID： 12100139 DOI： 10.1046/j.1365-2141.2002.03650.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998