| Literature DB >> 12099683 |
Sun Mi Lee1, Gregor Grass, Christopher Rensing, Siobhán R Barrett, Christopher J D Yates, Jivko V Stoyanov, Nigel L Brown.
Abstract
The interactions between the plasmid-borne copper resistance determinant, pco, and the main copper export system in Escherichia coli have been investigated and no direct interaction has been found. The PcoE and PcoC proteins are periplasmic and PcoC binds one Cu ion per protein molecule. PcoA is also periplasmic and can substitute for the chromosomally encoded CueO protein. The pco determinant is proposed to exert its effect through periplasmic handling of excess copper ions and to increase the level of resistance to copper ions above that conferred by copA alone. (c) 2002 Elsevier Science (USA).Entities:
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Year: 2002 PMID： 12099683 DOI： 10.1016/s0006-291x(02)00726-x
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575