| Literature DB >> 12098330 |
Marielle Lambers1, Felix H Beijer, José M Padron, Imre Toth, Johannes G de Vries.
Abstract
The four naturally occurring cinchona alkaloids were subjected to hydroformylation to create an extra functional group that allows immobilization. Cinchonidine, quinine, and quinidine, could be hydroformylated with virtually complete terminal selectivity, using a rhodium/tetraphosphite catalyst. The cinchonidine aldehyde was reduced to the alcohol and subjected to reductive amination with benzylamine.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12098330 DOI： 10.1021/jo0255173
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354