Literature DB >> 12097985

The importance of HLA DQB1*0602 typing in Slovene patients with narcolepsy.

Leja Dolenc-Grosel1, David B Vodusek.   

Abstract

The HLA class II region genes DQB1*0602 and DQA1*0102 are currently the best genetic predictors for narcolepsy in humans (1(. The aim of this study was to identify the HLA DQ alleles (DQB1*0602 and DQA1*0102) in Slovene sporadic narcoleptic patients. 11 patients who fulfilled ICSD criteria for narcolepsy entered the study. DRB1*1501 DQB1*0602 was present in all the patients while DQA1*0102 was absent in 2 patients. We propose that DQB1*0602 typing is important in diagnosing narcolepsy in Slovene patients

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Year:  2002        PMID: 12097985

Source DB:  PubMed          Journal:  Cell Mol Biol Lett        ISSN: 1425-8153            Impact factor:   5.787


  1 in total

1.  HLA-DQB1*06:02 allele frequency and clinic-polysomnographic features in Saudi Arabian patients with narcolepsy.

Authors:  Saad M Al Shareef; Eiman AlAnbay; Mujahed A AlKhathlan; Zahid Shakoor; Mustafa Alnasser; Khalid D Hamam; Adel S Alharbi; Aljohara S Almeneessier; Ahmed S BaHammam
Journal:  Sleep Breath       Date:  2018-09-05       Impact factor: 2.816

  1 in total

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