AIM: Intima-media thickness (IMT) has been shown to be useful in the evaluation and monitoring of carotid artery atherosclerosis in patients at risk of cardiovascular events. In this study, we aimed to examine the IMT in patients with nasopharyngeal carcinoma (NPC) who received irradiation to the carotid arteries during radiotherapy, and compared them with a control group. MATERIALS AND METHODS: Fifty-one NPC patients (aged between 39 and 69 years) and a group of 51 age-and sex-matched controls were studied by ultrasound. The IMT at the far wall of the common carotid artery was measured three times and the average value taken in each subject. The IMT of both groups were compared. Risk factors for IMT thickness, including hypertension, smoking, hyperglycaemia, hypercholesterolaemia, history of cerebrovascular accidents and cardiovascular disease, were also studied. RESULTS: The mean carotid IMT of patients in the NPC group (2.2+/-1.5 mm) was statistically greater than that in normal controls (0.7+/-0.15 mm) (P < 0.05). There was no statistically significant difference between the IMT in the right and left common carotid arteries within each group of patients. CONCLUSION: The findings suggest that patients with irradiation have increased arterial IMT. As they are asymptomatic the clinical relevance is not clear. Copyright 2002 The Royal College of Radiologists.
AIM: Intima-media thickness (IMT) has been shown to be useful in the evaluation and monitoring of carotid artery atherosclerosis in patients at risk of cardiovascular events. In this study, we aimed to examine the IMT in patients with nasopharyngeal carcinoma (NPC) who received irradiation to the carotid arteries during radiotherapy, and compared them with a control group. MATERIALS AND METHODS: Fifty-one NPCpatients (aged between 39 and 69 years) and a group of 51 age-and sex-matched controls were studied by ultrasound. The IMT at the far wall of the common carotid artery was measured three times and the average value taken in each subject. The IMT of both groups were compared. Risk factors for IMT thickness, including hypertension, smoking, hyperglycaemia, hypercholesterolaemia, history of cerebrovascular accidents and cardiovascular disease, were also studied. RESULTS: The mean carotid IMT of patients in the NPC group (2.2+/-1.5 mm) was statistically greater than that in normal controls (0.7+/-0.15 mm) (P < 0.05). There was no statistically significant difference between the IMT in the right and left common carotid arteries within each group of patients. CONCLUSION: The findings suggest that patients with irradiation have increased arterial IMT. As they are asymptomatic the clinical relevance is not clear. Copyright 2002 The Royal College of Radiologists.
Authors: Verónica Fernández-Alvarez; Fernando López; Carlos Suárez; Primoz Strojan; Avraham Eisbruch; Carl E Silver; William M Mendenhall; Johannes A Langendijk; Alessandra Rinaldo; Anne W M Lee; Jonathan J Beitler; Robert Smee; Javier Alvarez; Alfio Ferlito Journal: Strahlenther Onkol Date: 2018-04-20 Impact factor: 3.621
Authors: Kathleen A Meeske; Stuart E Siegel; Vicente Gilsanz; Leslie Bernstein; Mary B Nelson; Richard Sposto; Fred A Weaver; Robert S Lavey; M P H Wendy J Mack; Marvin D Nelson Journal: Pediatr Blood Cancer Date: 2009-10 Impact factor: 3.167
Authors: David I Rosenthal; Clifton D Fuller; Jerry L Barker; Bryan Mason; John A Garcia; Jan S Lewin; F Christopher Holsinger; C Richard Stasney; Steven J Frank; David L Schwartz; William H Morrison; Adam S Garden; K Kian Ang Journal: Int J Radiat Oncol Biol Phys Date: 2009-08-11 Impact factor: 7.038
Authors: Winnie X Y Zou; Thomas W Leung; Simon C H Yu; Edward H C Wong; S F Leung; Yannie O Y Soo; Vincent H L Ip; Anne Y Y Chan; Wynnie W M Lam; Deyond Y W Siu; Jill Abrigo; Kwok Tung Lee; David S Liebeskind; Ka Sing Wong Journal: Stroke Date: 2013-01-10 Impact factor: 7.914
Authors: D Strüder; S Hellwig; H Rennau; S van Bonn; S P Schraven; R Mlynski; G Hildebrandt; T Schuldt Journal: Eur Arch Otorhinolaryngol Date: 2020-09-01 Impact factor: 2.503