Literature DB >> 12095491

Hereditary thrombophilias are not associated with a decreased live birth rate in women with recurrent miscarriage.

Howard Carp1, Mordechai Dolitzky, Ilan Tur-Kaspa, Aida Inbal.   

Abstract

OBJECTIVE: To assesses the live birth rate without treatment in women with hereditary thrombophilia who have recurrent miscarriage and women without thrombophilia who have recurrent miscarriage.
DESIGN: Prospective observational study.
SETTING: Tertiary referral unit in university hospital. PATIENT(S): One hundred twenty women with thrombophilia and 65 women without thrombophilia. MAIN OUTCOME MEASURE(S): Number of live births or repeated miscarriages.
RESULTS: Of the 185 patients, 44 with thrombophilia and 26 without thrombophilia have conceived. Nineteen of the 44 pregnancies (43.2%) in thrombophilia patients have terminated in live births, compared with 8 of 26 pregnancies (30.8%) in patients without thrombophilia. This difference is not statistically significant.
CONCLUSIONS: Hereditary thrombophilia did not seem to affect the live birth rate in women with recurrent miscarriage.

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Year:  2002        PMID: 12095491     DOI: 10.1016/s0015-0282(02)03152-7

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  1 in total

1.  Prevalence of thromogenic gene mutations in women with recurrent miscarriage: A retrospective study of 1,507 patients.

Authors:  Adnan Incebiyik; Nese Gul Hilali; Aysun Camuzcuoglu; Hakan Camuzcuoglu; Halit Akbas; Avni Kilic; Mehmet Vural
Journal:  Obstet Gynecol Sci       Date:  2014-11-20
  1 in total

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