Literature DB >> 12095277

Analysis of complex methylation data.

Kimberly D Siegmund1, Peter W Laird.   

Abstract

The development of multiple DNA methylation analysis techniques, including higher-throughput assays, has resulted in data structures of increasing complexity and diversity. Here, we discuss the general principles of DNA methylation analysis and propose a nomenclature for the various types of methylation analysis. We briefly outline several DNA methylation analysis techniques and discuss how these different technologies affect the structure of the resulting methylation data. We then describe the basic statistics and bioinformatic principles relevant to the analysis of simple and complex methylation data. (c) 2002 Elsevier Science (USA).

Mesh：

Substances：

Year:  2002        PMID： 12095277     DOI： 10.1016/s1046-2023(02)00071-3

Source DB:  PubMed          Journal:  Methods        ISSN： 1046-2023            Impact factor:   3.608


  7 in total

1.  LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.

Authors:  Ana Aparicio; Brittany North; Lindsey Barske; Xuemei Wang; Valentina Bollati; Daniel Weisenberger; Christine Yoo; Nizar Tannir; Erin Horne; Susan Groshen; Peter Jones; Allen Yang; Jean-Pierre Issa
Journal:  Epigenetics       Date:  2009-04-06       Impact factor: 4.528

2.  Gene environment interactions with a novel variable Monoamine Oxidase A transcriptional enhancer are associated with antisocial personality disorder.

Authors:  Robert A Philibert; Pamela Wernett; Jeff Plume; Hans Packer; Gene H Brody; Steven R H Beach
Journal:  Biol Psychol       Date:  2011-05-07       Impact factor: 3.251

3.  Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome.

Authors:  Andreas Plagemann; Thomas Harder; Matthias Brunn; Anja Harder; Katharina Roepke; Manon Wittrock-Staar; Thomas Ziska; Karen Schellong; Elke Rodekamp; Kerstin Melchior; Joachim W Dudenhausen
Journal:  J Physiol       Date:  2009-09-01       Impact factor: 5.182

4.  Analysis of repetitive element DNA methylation by MethyLight.

Authors:  Daniel J Weisenberger; Mihaela Campan; Tiffany I Long; Myungjin Kim; Christian Woods; Emerich Fiala; Melanie Ehrlich; Peter W Laird
Journal:  Nucleic Acids Res       Date:  2005-12-02       Impact factor: 16.971

5.  Simultaneous statistical inference for epigenetic data.

Authors:  Konstantin Schildknecht; Sven Olek; Thorsten Dickhaus
Journal:  PLoS One       Date:  2015-05-12       Impact factor: 3.240

Review 6.  DNA Methylation in Lung Cancer: Mechanisms and Associations with Histological Subtypes, Molecular Alterations, and Major Epidemiological Factors.

Authors:  Phuc H Hoang; Maria Teresa Landi
Journal:  Cancers (Basel)       Date:  2022-02-15       Impact factor: 6.639

Review 7.  DNA methylation in peripheral blood: a potential biomarker for cancer molecular epidemiology.

Authors:  Lian Li; Ji-Yeob Choi; Kyoung-Mu Lee; Hyuna Sung; Sue K Park; Isao Oze; Kai-Feng Pan; Wei-Cheng You; Ying-Xuan Chen; Jing-Yuan Fang; Keitaro Matsuo; Woo Ho Kim; Yasuhito Yuasa; Daehee Kang
Journal:  J Epidemiol       Date:  2012-08-04       Impact factor: 3.211
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.