| Literature DB >> 12094307 |
Jae-Taek Han, Hae-Yeong Kim, Young-Doo Park, Youn-Hyung Lee, Kang-Ro Lee, Byoung-Mog Kwon, Nam-In Baek.
Abstract
Two new triterpenoids along with three known ones, 3-oxoolean-12-en-27-oic acid (1), 3alpha-hydroxyolean-12-en-27-oic acid (2) and 3beta-hydroxyolean-12-en-27-oic acid (3), were isolated from Aceriphyllum rossii. The structures of the new compounds were determined to be a 3alpha,23-dihydroxyolean-12-en-27-oic acid (4) and a 3alpha,23-dihydroxyolean-12-en-29-oic acid (5) by spectroscopic and chemical methods; they were designated aceriphyllic acids A and B, respectively. Compounds 2, 3 and 4 remarkably inhibited the activity of ACAT.Entities:
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Year: 2002 PMID： 12094307 DOI： 10.1055/s-2002-32565
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352