Literature DB >> 12094302

Inhibitory effects of natural sesquiterpenoids isolated from the rhizomes of Curcuma zedoaria on prostaglandin E2 and nitric oxide production.

Chae Hee Hong, Min Soo Noh, Woo Young Lee, Sang Kook Lee.   

Abstract

Beta-turmerone and ar-turmerone, sesquiterpenoids isolated from the rhizome of Curcuma zedoaria, inhibited lipopolysaccharide (LPS)-induced prostaglandin E 2 production in cultured mouse macrophage cell RAW 264.7 in a dose-dependent manner (IC 50 = 7.3 microM for beta-turmerone; IC 50 = 24.0 microM for ar-turmerone). In addition, these compounds exhibited inhibitory effects on LPS-induced nitric oxide production in the cell system.

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Year:  2002        PMID： 12094302     DOI： 10.1055/s-2002-32560

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  5 in total

1.  Anti-arthritic effects and toxicity of the essential oils of turmeric (Curcuma longa L.).

Authors:  Janet L Funk; Jennifer B Frye; Janice N Oyarzo; Huaping Zhang; Barbara N Timmermann
Journal:  J Agric Food Chem       Date:  2010-01-27       Impact factor: 5.279

2.  The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice.

Authors:  Cheong-Su Eun; Jong-Soon Lim; Jihye Lee; Sam-Pin Lee; Seun-Ah Yang
Journal:  BMC Complement Altern Med       Date:  2017-07-17       Impact factor: 3.659

Review 3.  Molecular mechanism underlying anti-inflammatory and anti-allergic activities of phytochemicals: an update.

Authors:  Yuva Bellik; Laïd Boukraâ; Hasan A Alzahrani; Balkees A Bakhotmah; Fatiha Abdellah; Si M Hammoudi; Mokrane Iguer-Ouada
Journal:  Molecules       Date:  2012-12-27       Impact factor: 4.411

4.  Molecular Hybridization-Guided One-Pot Multicomponent Synthesis of Turmerone Motif-Fused 3,3'-Pyrrolidinyl-dispirooxindoles via a 1,3-Dipolar Cycloaddition Reaction.

Authors:  Bing Lin; Gen Zhou; Yi Gong; Qi-Di Wei; Min-Yi Tian; Xiong-Li Liu; Ting-Ting Feng; Ying Zhou; Wei-Cheng Yuan
Journal:  Molecules       Date:  2017-04-17       Impact factor: 4.411

5.  Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells.

Authors:  S Lakshmi; G Padmaja; P Remani
Journal:  Int J Med Chem       Date:  2011-02-15
  5 in total

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