Literature DB >> 12094235

The phosphatidylinositol 3-Kinase AKT pathway in human cancer.

Igor Vivanco1, Charles L Sawyers.   

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Year:  2002        PMID: 12094235     DOI: 10.1038/nrc839

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


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  2000 in total

1.  Effect of uraemia on endothelial cell damage is mediated by the integrin linked kinase pathway.

Authors:  Andrea García-Jérez; Alicia Luengo; Julia Carracedo; Rafael Ramírez-Chamond; Diego Rodriguez-Puyol; Manuel Rodriguez-Puyol; Laura Calleros
Journal:  J Physiol       Date:  2014-12-18       Impact factor: 5.182

Review 2.  Exploiting novel molecular targets in gastrointestinal cancers.

Authors:  Wen W Ma; Manuel Hidalgo
Journal:  World J Gastroenterol       Date:  2007-11-28       Impact factor: 5.742

Review 3.  Programmed cell death and new discoveries in the genetics of parkinsonism.

Authors:  Robert E Burke
Journal:  J Neurochem       Date:  2007-12-10       Impact factor: 5.372

4.  Naproxen induces cell-cycle arrest and apoptosis in human urinary bladder cancer cell lines and chemically induced cancers by targeting PI3K.

Authors:  Mi-Sung Kim; Jong-Eun Kim; Do Young Lim; Zunnan Huang; Hanyong Chen; Alyssa Langfald; Ronald A Lubet; Clinton J Grubbs; Zigang Dong; Ann M Bode
Journal:  Cancer Prev Res (Phila)       Date:  2013-12-10

5.  Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.

Authors:  Linhua Jin; Yoko Tabe; Hongbo Lu; Gautam Borthakur; Takashi Miida; Hagop Kantarjian; Michael Andreeff; Marina Konopleva
Journal:  Cancer Lett       Date:  2012-10-02       Impact factor: 8.679

6.  The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.

Authors:  Xavier Leleu; Xiaoying Jia; Judith Runnels; Hai T Ngo; Anne-Sophie Moreau; Mena Farag; Joel A Spencer; Costas M Pitsillides; Evdoxia Hatjiharissi; Aldo Roccaro; Garrett O'Sullivan; Douglas W McMillin; Daisy Moreno; Tanyel Kiziltepe; Ruben Carrasco; Steven P Treon; Teru Hideshima; Kenneth C Anderson; Charles P Lin; Irene M Ghobrial
Journal:  Blood       Date:  2007-08-30       Impact factor: 22.113

Review 7.  Interlinking interleukin-7.

Authors:  Christina Kittipatarin; Annette R Khaled
Journal:  Cytokine       Date:  2007-09-04       Impact factor: 3.861

Review 8.  A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction.

Authors:  Winston Timp; Andre Levchenko; Andrew P Feinberg
Journal:  Cell Cycle       Date:  2009-02-03       Impact factor: 4.534

9.  Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents.

Authors:  Katherine J Kayser-Bricker; Matthew P Glenn; Sang Hoon Lee; Said M Sebti; Jin Q Cheng; Andrew D Hamilton
Journal:  Bioorg Med Chem       Date:  2008-09-27       Impact factor: 3.641

10.  Nuclear accumulation of cyclin D1 following long-term fractionated exposures to low-dose ionizing radiation in normal human diploid cells.

Authors:  Tsutomu Shimura; Nobuyuki Hamada; Megumi Sasatani; Kenji Kamiya; Naoki Kunugita
Journal:  Cell Cycle       Date:  2014-02-14       Impact factor: 4.534

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