Literature DB >> 12093884

Human CYP7A1 deficiency: progress and enigmas.

Anne Beigneux1, Alan F Hofmann, Stephen G Young.   

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Year:  2002        PMID: 12093884      PMCID: PMC151039          DOI: 10.1172/JCI16076

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  26 in total

1.  Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study.

Authors:  P Couture; J D Otvos; L A Cupples; P W Wilson; E J Schaefer; J M Ordovas
Journal:  J Lipid Res       Date:  1999-10       Impact factor: 5.922

2.  Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.

Authors:  M Schwarz; D W Russell; J M Dietschy; S D Turley
Journal:  J Lipid Res       Date:  2001-10       Impact factor: 5.922

3.  Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids.

Authors:  H R Kast; C M Nguyen; C J Sinal; S A Jones; B A Laffitte; K Reue; F J Gonzalez; T M Willson; P A Edwards
Journal:  Mol Endocrinol       Date:  2001-10

4.  27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.

Authors:  X Fu; J G Menke; Y Chen; G Zhou; K L MacNaul; S D Wright; C P Sparrow; E G Lund
Journal:  J Biol Chem       Date:  2001-08-14       Impact factor: 5.157

5.  Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

Authors:  J J Repa; E G Lund; J D Horton; E Leitersdorf; D W Russell; J M Dietschy; S D Turley
Journal:  J Biol Chem       Date:  2000-12-15       Impact factor: 5.157

6.  Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype.

Authors:  Clive R Pullinger; Celeste Eng; Gerald Salen; Sarah Shefer; Ashok K Batta; Sandra K Erickson; Andrea Verhagen; Christopher R Rivera; Sean J Mulvihill; Mary J Malloy; John P Kane
Journal:  J Clin Invest       Date:  2002-07       Impact factor: 14.808

7.  Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;.

Authors:  K Einarsson; K Hellström; M Kallner
Journal:  J Clin Invest       Date:  1974-12       Impact factor: 14.808

8.  Effects of interruption of the enterohepatic circulation of bile acids on the transport of very low density-lipoprotein triglycerides.

Authors:  U Beil; J R Crouse; K Einarsson; S M Grundy
Journal:  Metabolism       Date:  1982-05       Impact factor: 8.694

9.  Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26.

Authors:  G Salen; S Shefer; G S Tint; G Nicolau; B Dayal; A K Batta
Journal:  J Clin Invest       Date:  1985-08       Impact factor: 14.808

10.  Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis.

Authors:  R Wang; M Salem; I M Yousef; B Tuchweber; P Lam; S J Childs; C D Helgason; C Ackerley; M J Phillips; V Ling
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-06       Impact factor: 11.205

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  5 in total

1.  The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.

Authors:  Kevin M Beggs; Steven R McGreal; Alex McCarthy; Sumedha Gunewardena; Jed N Lampe; Christoper Lau; Udayan Apte
Journal:  Toxicol Appl Pharmacol       Date:  2016-05-03       Impact factor: 4.219

Review 2.  Primary biliary cholangitis: pathogenesis and therapeutic opportunities.

Authors:  Aliya F Gulamhusein; Gideon M Hirschfield
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2019-12-09       Impact factor: 46.802

3.  Comparative antilipidemic effect of N-acetylcysteine and sesame oil administration in diet-induced hypercholesterolemic mice.

Authors:  Laskarina-Maria Korou; George Agrogiannis; Alkisti Pantopoulou; Ioannis S Vlachos; Dimitrios Iliopoulos; Theodoros Karatzas; Despoina N Perrea
Journal:  Lipids Health Dis       Date:  2010-03-06       Impact factor: 3.876

4.  Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

Authors:  Mitsuhiro Watanabe; Sander M Houten; Li Wang; Antonio Moschetta; David J Mangelsdorf; Richard A Heyman; David D Moore; Johan Auwerx
Journal:  J Clin Invest       Date:  2004-05       Impact factor: 14.808

5.  MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1.

Authors:  Ruijie Gong; Xiaofei Lv; Fengqiong Liu
Journal:  Cell Mol Biol Lett       Date:  2018-04-18       Impact factor: 5.787

  5 in total

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