Literature DB >> 12093880

The therapeutic potential of modulating the ceramide/sphingomyelin pathway.

Richard Kolesnick1.   

Abstract

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Year:  2002        PMID： 12093880      PMCID： PMC151041          DOI： 10.1172/JCI16127

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  61 in total

1.  Molecular cloning and characterization of a human mitochondrial ceramidase.

Authors:  S El Bawab; P Roddy; T Qian; A Bielawska; J J Lemasters; Y A Hannun
Journal:  J Biol Chem       Date:  2000-07-14       Impact factor: 5.157

2.  Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.

Authors:  R M Siegel; J K Frederiksen; D A Zacharias; F K Chan; M Johnson; D Lynch; R Y Tsien; M J Lenardo
Journal:  Science       Date:  2000-06-30       Impact factor: 47.728

Review 3.  Compartmentalization of ceramide signaling: physical foundations and biological effects.

Authors:  R N Kolesnick; F M Goñi; A Alonso
Journal:  J Cell Physiol       Date:  2000-09       Impact factor: 6.384

4.  Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.

Authors:  Y Morita; G I Perez; F Paris; S R Miranda; D Ehleiter; A Haimovitz-Friedman; Z Fuks; Z Xie; J C Reed; E H Schuchman; R N Kolesnick; J L Tilly
Journal:  Nat Med       Date:  2000-10       Impact factor: 53.440

Review 5.  How cells handle cholesterol.

Authors:  K Simons; E Ikonen
Journal:  Science       Date:  2000-12-01       Impact factor: 47.728

6.  The 1999 Moyer award. Burn injury induces skeletal muscle apoptosis and the activation of caspase pathways in rats.

Authors:  S Yasuhara; E Kanakubo; M E Perez; M Kaneki; T Fujita; T Okamoto; J A Martyn
Journal:  J Burn Care Rehabil       Date:  1999 Nov-Dec

7.  Cathepsin D targeted by acid sphingomyelinase-derived ceramide.

Authors:  M Heinrich; M Wickel; W Schneider-Brachert; C Sandberg; J Gahr; R Schwandner; T Weber; P Saftig; C Peters; J Brunner; M Krönke; S Schütze
Journal:  EMBO J       Date:  1999-10-01       Impact factor: 11.598

8.  Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line.

Authors:  S Mehta; D Blackinton; I Omar; N Kouttab; D Myrick; J Klostergaard; H Wanebo
Journal:  Cancer Chemother Pharmacol       Date:  2000       Impact factor: 3.333

9.  Ceramide-coated balloon catheters limit neointimal hyperplasia after stretch injury in carotid arteries.

Authors:  R Charles; L Sandirasegarane; J Yun; N Bourbon; R Wilson; R P Rothstein; S W Levison; M Kester
Journal:  Circ Res       Date:  2000-08-18       Impact factor: 17.367

10.  Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.

Authors:  H Liu; M Sugiura; V E Nava; L C Edsall; K Kono; S Poulton; S Milstien; T Kohama; S Spiegel
Journal:  J Biol Chem       Date:  2000-06-30       Impact factor: 5.157
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  134 in total

1.  Alpha particles induce apoptosis through the sphingomyelin pathway.

Authors:  Jonathan H Seideman; Branka Stancevic; Jimmy A Rotolo; Michael R McDevitt; Roger W Howell; Richard N Kolesnick; David A Scheinberg
Journal:  Radiat Res       Date:  2011-06-01       Impact factor: 2.841

2.  Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain.

Authors:  Rotem Tidhar; Shifra Ben-Dor; Elaine Wang; Samuel Kelly; Alfred H Merrill; Anthony H Futerman
Journal:  J Biol Chem       Date:  2011-12-05       Impact factor: 5.157

3.  Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).

Authors:  Jennifer L Kielczewski; Sergio Li Calzi; Lynn C Shaw; Jun Cai; Xiaoping Qi; Qing Ruan; Lin Wu; Li Liu; Ping Hu; Tailoi Chan-Ling; Robert N Mames; Sue Firth; Robert C Baxter; Patric Turowski; Julia V Busik; Michael E Boulton; Maria B Grant
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-10-21       Impact factor: 4.799

Review 4.  Roles of reactive oxygen and nitrogen species in pain.

Authors:  Daniela Salvemini; Joshua W Little; Timothy Doyle; William L Neumann
Journal:  Free Radic Biol Med       Date:  2011-01-28       Impact factor: 7.376

Review 5.  Cholesterol, lipid rafts, and disease.

Authors:  Kai Simons; Robert Ehehalt
Journal:  J Clin Invest       Date:  2002-09       Impact factor: 14.808

Review 6.  The role of cholesterol efflux in regulating the fertilization potential of mammalian spermatozoa.

Authors:  Alexander J Travis; Gregory S Kopf
Journal:  J Clin Invest       Date:  2002-09       Impact factor: 14.808

7.  Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis.

Authors:  Ching G Ng; Diane E Griffin
Journal:  J Virol       Date:  2006-08-30       Impact factor: 5.103

8.  Changes in ceramide metabolism are essential in Madin-Darby canine kidney cell differentiation.

Authors:  Lucila Gisele Pescio; Bruno Jaime Santacreu; Vanina Gisela Lopez; Carlos Humberto Paván; Daniela Judith Romero; Nicolás Octavio Favale; Norma Beatriz Sterin-Speziale
Journal:  J Lipid Res       Date:  2017-05-17       Impact factor: 5.922

9.  Interleukin-6 changes tight junction permeability and intracellular phospholipid content in a human enterocyte cell culture model.

Authors:  Y Tazuke; R A Drongowski; D H Teitelbaum; A G Coran
Journal:  Pediatr Surg Int       Date:  2003-05-06       Impact factor: 1.827

10.  Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice.

Authors:  Carmen García-Ruiz; Anna Colell; Montserrat Marí; Albert Morales; María Calvo; Carlos Enrich; José C Fernández-Checa
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808
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