| Literature DB >> 12092820 |
Masayuki Okue1, Hidenori Watanabe, Koji Kasahara, Minoru Yoshida, Sueharu Horinouchi, Takeshi Kitahara.
Abstract
All the eight stereoisomers of (+)-preussin (1b), an antifungal agent inhibiting the growth of fission yeast and human cancer cells, were synthesized in two steps by non-stereoselective reactions and chromatographic separation, starting from L- and D-N-protected-phenylalaninal (2). Their bioassay revealed all of the stereoisomers to be almost equally bioactive.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12092820 DOI： 10.1271/bbb.66.1093
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043