Literature DB >> 12092641

Common conditions of the aging male: erectile dysfunction, benign prostatic hyperplasia, cardiovascular disease and depression.

L Zakaria1, A G Anastasiadis, R Shabsigh.   

Abstract

With increasing life expectancy, medical profession will be faced with the task of ensuring that the large, aging population remains healthy and vital despite the face of increasing healthcare costs. Naturally, urology as a specialty is concerned with important geriatric issues. This article will focus specifically on the aging male population and the health problems that most frequently plague them. Four major, non-cancer, disease states have been identified that adversely effect males over the age of 50. These conditions are: erectile dysfunction (ED), benign prostatic hyperplasia (BPH), cardiovascular disease (CVD) and depression. A literature search of PubMed was conducted using the key words ED, BPH, CVD and depression as well as ADAM (Androgen Decline in the Aging Male) and quality of life (QoL). NIH and WHO conference proceedings and publications were also referenced to insure detail and accuracy of data. Information was then organized and correlated in order to provide a detailed description of the key conditions and their interrelatedness. The spectrum of research performed thus far regarding this topic has done little to investigate the effects, causes and correlations between these conditions. Research has been done linking two or three of these conditions; however, there remains to be information discussing the four disease states in terms of their possible cause and effect relationships or the effectiveness of parallel, multi-disciplinary approach to their therapy. This report calls attention to the benefits of viewing and researching the above mentioned conditions as possibly interrelated, as opposed to the traditional view of them as separate, unrelated and independently treatable disease states. ED, BPH, CVD and depression are all common conditions that accompany aging and negatively impact QoL. They almost always develop with age and precipitate considerable morbidity and may even result in mortality. Furthermore, the presentation of one condition may correlate with the development of another. The inter-relation of these conditions, as evident from their underlying similarities, cause-and-effects relationships and therapeutic consequences, should be enough to warrant a multidisciplinary approach to their research. This approach, combined with careful choice of therapy, parallel and singular, will help providers reach their goal to keep patients healthy, and more importantly happy, late into their life, thus realizing the concept of "successful aging".

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Year:  2001        PMID: 12092641     DOI: 10.1023/a:1015292603884

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  67 in total

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Review 3.  Andropause: a misnomer for a true clinical entity.

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Journal:  Fam Pract       Date:  1997-12       Impact factor: 2.267

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Review 9.  Treating the depressed patient with cardiovascular problems.

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Journal:  Urology       Date:  1998-11       Impact factor: 2.649

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  7 in total

1.  An open, comparative, multicentre clinical study of combined oral therapy with sildenafil and doxazosin GITS for treating Chinese patients with erectile dysfunction and lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Authors:  Zhe Jin; Zhi-Chao Zhang; Ji-Hong Liu; Jun Lu; Yu-Xin Tang; Xiang-Zhou Sun; Wei-Dong Song; Bing Gao; Ying-Lu Guo; Zhong-Cheng Xin
Journal:  Asian J Androl       Date:  2011-05-23       Impact factor: 3.285

2.  Are lower urinary tract symptoms associated with cardiovascular disease in the Dutch general population? Results from the Krimpen study.

Authors:  Inge I Bouwman; Marco H Blanker; Boris W V Schouten; Arthur M Bohnen; Rien J M Nijman; Wouter K van der Heide; J L H Ruud Bosch
Journal:  World J Urol       Date:  2014-09-25       Impact factor: 4.226

3.  The cardiovascular risk factors in men with lower urinary tract symptoms.

Authors:  Chi-Hang Yee; Jenny S Y Yip; Nicole M Y Cheng; Cheuk-Hang Kwan; Kai-Man Li; Jeremy Y C Teoh; Peter K F Chiu; Joseph Hon-Ming Wong; Eddie S Y Chan; Chi-Kwok Chan; Simon S M Hou; Chi-Fai Ng
Journal:  World J Urol       Date:  2018-08-06       Impact factor: 4.226

Review 4.  Understanding the needs and objectives of erectile dysfunction patients.

Authors:  Ridwan Shabsigh; Brian Stone
Journal:  World J Urol       Date:  2006-12       Impact factor: 3.661

5.  Holter Monitoring (24-Hour ECG) Parameter Dynamics in Patients with Ischemic Heart Disease and Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia.

Authors:  Dmitrii N Fiev; Andrey Z Vinarov; Dmitrii G Tsarichenko; Phillip Yu Kopylov; Yuri L Demidko; Abram L Syrkin; Leonid M Rapoport; Yuri G Alyaev; Pyotr V Glybochko
Journal:  Adv Ther       Date:  2019-05-30       Impact factor: 3.845

6.  Effects of oxybutynin transdermal system on health-related quality of life and safety in men with overactive bladder and prostate conditions.

Authors:  D R Staskin; M T Rosenberg; N V Dahl; P V Polishuk; N R Zinner
Journal:  Int J Clin Pract       Date:  2007-11-15       Impact factor: 2.503

7.  Are lower urinary tract symptoms in men associated with cardiovascular diseases in a primary care population: a registry study.

Authors:  Inge I Bouwman; Boudewijn J Kollen; Klaas van der Meer; Rien J M Nijman; Wouter K van der Heide
Journal:  BMC Fam Pract       Date:  2014-01-14       Impact factor: 2.497

  7 in total

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