| Literature DB >> 12089131 |
J Zschocke1, S Schindler, G F Hoffmann, M Albani.
Abstract
We report on a child in whom severe nutritional vitamin B12 deficiency was exacerbated by a genetic impairment of the folate cycle, causing reduced CSF concentrations of the methyl group donor 5-methyltetrahydrofolate. Some patients with vitamin B12 deficiency may benefit from high dose folic acid supplementation, even if plasma concentrations are high.Entities:
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Year: 2002 PMID： 12089131 PMCID： PMC1751157 DOI： 10.1136/adc.87.1.75
Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791