Literature DB >> 12088684

Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection.

Rajesh T Gandhi1, Bruce D Walker.   

Abstract

Recent studies suggest that immunologic containment of HIV-1 is possible and the immune correlates of this control are being defined. There have been significant advances in our ability to elicit virus-specific immune responses, which have led to viral control in animal models. Although viral escape from the immune system is an important challenge, new strategies for therapeutic and preventative HIV-1 vaccination are being vigorously pursued in human trials.

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Year:  2002        PMID： 12088684     DOI： 10.1016/s0952-7915(02)00359-x

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  5 in total

1.  Enhancement of gp120-specific immune responses by genetic vaccination with the human immunodeficiency virus type 1 envelope gene fused to the gene coding for soluble CTLA4.

Authors:  Bishnu P Nayak; Gangadhara Sailaja; Abdul M Jabbar
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

2.  Growth hormone enhances thymic function in HIV-1-infected adults.

Authors:  Laura A Napolitano; Diane Schmidt; Michael B Gotway; Niloufar Ameli; Erin L Filbert; Myra M Ng; Julie L Clor; Lorrie Epling; Elizabeth Sinclair; Paul D Baum; Kai Li; Marisela Lua Killian; Peter Bacchetti; Joseph M McCune
Journal:  J Clin Invest       Date:  2008-03       Impact factor: 14.808

3.  Kunjin virus replicon vectors for human immunodeficiency virus vaccine development.

Authors:  Tracey J Harvey; Itaru Anraku; Richard Linedale; David Harrich; Jason Mackenzie; Andreas Suhrbier; Alexander A Khromykh
Journal:  J Virol       Date:  2003-07       Impact factor: 5.103

4.  Structured Treatment Interruptions and Low Doses of IL-2 in Patients with Primary HIV Infection. Inflammatory, Virological and Immunological Outcomes.

Authors:  Omar Sued; Juan Ambrosioni; David Nicolás; Christian Manzardo; Fernando Agüero; Xavier Claramonte; Montserrat Plana; Montserrat Tuset; Tomás Pumarola; Teresa Gallart; José María Gatell; José María Miró
Journal:  PLoS One       Date:  2015-07-17       Impact factor: 3.240

5.  Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.

Authors:  Sang-Jun Ha; Scott N Mueller; E John Wherry; Daniel L Barber; Rachael D Aubert; Arlene H Sharpe; Gordon J Freeman; Rafi Ahmed
Journal:  J Exp Med       Date:  2008-03-10       Impact factor: 14.307
  5 in total

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