Literature DB >> 12088441

Lyngbouilloside, a novel glycosidic macrolide from the marine cyanobacterium Lyngbya bouillonii.

Lik Tong Tan1, Brian L Márquez, William H Gerwick.   

Abstract

A glycosidic macrolide, lyngbouilloside (1), was characterized from the marine cyanobacterium Lyngbya bouillonii collected from Papua New Guinea. Its structure was elucidated by spectroscopic analysis and chemical derivatization. Relative stereochemistry was deduced from homonuclear and heteronuclear coupling constants as well as NOE information. Lyngbouilloside was modestly cytotoxic to neuroblastoma cells (IC(50) value of 17 microM).

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Year:  2002        PMID: 12088441     DOI: 10.1021/np010526c

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  19 in total

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5.  Total synthesis and structure-activity investigation of the marine natural product neopeltolide.

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7.  Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam.

Authors:  Susan Matthew; Lilibeth A Salvador; Peter J Schupp; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2010-09-24       Impact factor: 4.050

8.  Synthetic Studies to Lyngbouilloside: A Phosphate Tether-Mediated Synthesis of the Macrolactone Core.

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Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

9.  Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii.

Authors:  Irma E Soria-Mercado; Alban Pereira; Zhengyu Cao; Thomas F Murray; William H Gerwick
Journal:  Org Lett       Date:  2009-10-15       Impact factor: 6.005

10.  Dual macrolactonization/pyran-hemiketal formation via acylketenes: applications to the synthesis of (-)-callipeltoside A and a lyngbyaloside B model system.

Authors:  Thomas R Hoye; Michael E Danielson; Aaron E May; Hongyu Zhao
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