| Literature DB >> 1208598 |
T Asano, M Pollard, D C Madsen.
Abstract
Oral administration of 1,2-dimethylhydrazine (DMH) induced intestinal neoplasms in germfree rats. A supplement of 2% cholestyramine resin in the diet increased the frequency of DMH-induced intestinal tumors and accelerated malignant transformation. Bile acids in the cecal content were determined with and without cholestyramine in order to obtain a correlation between the bile acid metabolism and the enteric carcinogenesis.Entities:
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Year: 1975 PMID： 1208598 DOI： 10.3181/00379727-150-39124
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727