Literature DB >> 12084222

A novel method for the analysis of the androgen receptor.

Kris E Gaston1, O Harris Ford III, Swaroop Singh, Christopher W Gregory, Donald E Weyel, Gary J Smith, James L Mohler.   

Abstract

The role of the androgen receptor in the regulation of prostate cancer development and progression has been a focus of intense research. Until recent years, the level of expression of the androgen receptor protein was described qualitatively. Immunohistochemical parameters have been established that show a linear relationship between androgen receptor expression and immunostaining. Intensity of immunostaining can be accurately measured using computer-assisted color video image analysis. Studies of progression and treatment of prostate cancer will benefit from the ability to quantitatively measure androgen receptor expression.

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Year:  2002        PMID： 12084222     DOI： 10.1007/s11934-002-0013-8

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN： 1527-2737            Impact factor:   2.862


  39 in total

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Journal:  J Biol Chem       Date:  1969-12-25       Impact factor: 5.157

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Journal:  J Neurosci Methods       Date:  1988-11       Impact factor: 2.390

Review 3.  Molecular mechanisms of action of steroid/thyroid receptor superfamily members.

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Journal:  Annu Rev Biochem       Date:  1994       Impact factor: 23.643

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Authors:  G S Prins; R J Sklarew; L P Pertschuk
Journal:  J Urol       Date:  1998-03       Impact factor: 7.450

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Authors:  N D Zegers; E Claassen; C Neelen; E Mulder; J H van Laar; M M Voorhorst; C A Berrevoets; A O Brinkmann; T H van der Kwast; J A Ruizeveld de Winter
Journal:  Biochim Biophys Acta       Date:  1991-01-23

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Journal:  Mod Pathol       Date:  1997-08       Impact factor: 7.842

7.  Transcriptional activation modulated by homopolymeric glutamine and proline stretches.

Authors:  H P Gerber; K Seipel; O Georgiev; M Höfferer; M Hug; S Rusconi; W Schaffner
Journal:  Science       Date:  1994-02-11       Impact factor: 47.728

8.  The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer.

Authors:  R A Irvine; M C Yu; R K Ross; G A Coetzee
Journal:  Cancer Res       Date:  1995-05-01       Impact factor: 12.701

9.  Quantitative immunocytochemistry of tyrosine hydroxylase in rat brain. I. Development of a computer assisted method using the peroxidase-antiperoxidase technique.

Authors:  R H Benno; L W Tucker; T H Joh; D J Reis
Journal:  Brain Res       Date:  1982-08-26       Impact factor: 3.252

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Authors:  M A Wainstein; F He; D Robinson; H J Kung; S Schwartz; J M Giaconia; N L Edgehouse; T P Pretlow; D R Bodner; E D Kursh
Journal:  Cancer Res       Date:  1994-12-01       Impact factor: 12.701
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  2 in total

Review 1.  A role for the androgen-receptor in clinically localized and advanced prostate cancer.

Authors:  James L Mohler
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2008-04       Impact factor: 4.690

2.  Java Web Start based software for automated quantitative nuclear analysis of prostate cancer and benign prostate hyperplasia.

Authors:  Swaroop S Singh; Desok Kim; James L Mohler
Journal:  Biomed Eng Online       Date:  2005-05-11       Impact factor: 2.819
  2 in total

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