Literature DB >> 12083010

Immunological functions of the proteasome.

G Niedermann1.   

Abstract

Proteasomes are highly abundant cytosolic and nuclear protease complexes that degrade most intracellular proteins in higher eukaryotes and appear to play a major role in the cytosolic steps of MHC class I antigen processing. This review summarizes the knowledge of the role of proteasomes in antigen processing and the impact of proteasomal proteolysis on T cell-mediated immunity.

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Year:  2002        PMID： 12083010     DOI： 10.1007/978-3-642-59414-4_5

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN： 0070-217X            Impact factor:   4.291


  11 in total

1.  Phosphorylation of 20S proteasome alpha subunit C8 (alpha7) stabilizes the 26S proteasome and plays a role in the regulation of proteasome complexes by gamma-interferon.

Authors:  Suchira Bose; Fiona L L Stratford; Kerry I Broadfoot; Grant G F Mason; A Jennifer Rivett
Journal:  Biochem J       Date:  2004-02-15       Impact factor: 3.857

Review 2.  Overview of the immune response.

Authors:  David D Chaplin
Journal:  J Allergy Clin Immunol       Date:  2010-02       Impact factor: 10.793

3.  Insights into the molecular architecture of the 26S proteasome.

Authors:  Stephan Nickell; Florian Beck; Sjors H W Scheres; Andreas Korinek; Friedrich Förster; Keren Lasker; Oana Mihalache; Na Sun; István Nagy; Andrej Sali; Jürgen M Plitzko; Jose-Maria Carazo; Matthias Mann; Wolfgang Baumeister
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-06       Impact factor: 11.205

Review 4.  [The role of radiotherapy in the induction of antitumor immune responses].

Authors:  G Multhoff; U S Gaipl; G Niedermann
Journal:  Strahlenther Onkol       Date:  2012-11       Impact factor: 3.621

5.  Escape mutations alter proteasome processing of major histocompatibility complex class I-restricted epitopes in persistent hepatitis C virus infection.

Authors:  Yoichi Kimura; Toshifumi Gushima; Sharad Rawale; Pravin Kaumaya; Christopher M Walker
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

6.  Expression pattern of immunoproteasome subunits in human thymus.

Authors:  Kwon Ik Oh; Jae Nam Seo
Journal:  Immune Netw       Date:  2009-12-31       Impact factor: 6.303

7.  Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency.

Authors:  Ricardo F Frausto; Stephen J Crocker; Boreth Eam; Jason K Whitmire; J Lindsay Whitton
Journal:  J Neuroimmunol       Date:  2007-10-26       Impact factor: 3.478

8.  Differential proteasomal processing of hydrophobic and hydrophilic protein regions: contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef.

Authors:  Maria Lucchiari-Hartz; Viv Lindo; Niclas Hitziger; Simone Gaedicke; Loredana Saveanu; Peter M van Endert; Fiona Greer; Klaus Eichmann; Gabriele Niedermann
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-16       Impact factor: 11.205

9.  Concomitant differentiation and partial proteasome inhibition trigger apoptosis in neuroblastoma cells.

Authors:  Piruz Nahreini; Cynthia Andreatta; Amy Hanson; Kedar N Prasad
Journal:  J Neurooncol       Date:  2003-05       Impact factor: 4.130

10.  Conservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.

Authors:  Paul Thiamjoo Tan; A T Heiny; Olivo Miotto; Jerome Salmon; Ernesto T A Marques; Francois Lemonnier; J Thomas August
Journal:  PLoS One       Date:  2010-01-18       Impact factor: 3.240
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