Literature DB >> 12079867

Uncoupling proteins, leptin, and obesity: an updated review.

Jean-Paul Giacobino1.   

Abstract

The hypothesis that the novel uncoupling protein UCP3 is thermogenic and/or thermoregulatory is discussed. In vitro, ex vivo, and in vivo models are presented. The beta(3)-adrenoceptors are crucial for the appearance of UCP1-expressing cells in the white adipose tissue. These cells might differ from classical brown adipocytes. Besides its well-known effect on brown adipose tissue UCP1, leptin might stimulate indirectly muscle UCP3 expression.

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Year:  2002        PMID: 12079867     DOI: 10.1111/j.1749-6632.2002.tb04295.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  2 in total

1.  Ectopic UCP1 gene expression in HepG2 cells affects ATP production.

Authors:  P González-Muniesa; F I Milagro; J Campión; J A Martínez
Journal:  J Physiol Biochem       Date:  2005-06       Impact factor: 4.158

2.  Experimental hyperthyroidism decreases gene expression and serum levels of adipokines in obesity.

Authors:  Renata de Azevedo Melo Luvizotto; André Ferreira do Nascimento; Maria Teresa de Síbio; Regiane Marques Castro Olímpio; Sandro José Conde; Ana Paula Lima-Leopoldo; André Soares Leopoldo; Antonio Carlos Cicogna; Célia Regina Nogueira
Journal:  ScientificWorldJournal       Date:  2012-05-03
  2 in total

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