| Literature DB >> 12079836 |
Theodore P Ciaraldi1, Bong-Soo Cha, Kyong-Soo Park, Leslie Carter, Sunder R Mudaliar, Robert R Henry.
Abstract
Free fatty acid (FFA) oxidation in human skeletal muscle cells can be stimulated, both independently and in a synergistic manner, by agonists for PPARgamma and RXR. Increased FFA disposal in muscle through augmented oxidation could reduce intramyocellular lipid accumulation. The abilities of such agents to improve glucose tolerance and insulin action may thus involve effects on both glucose and FFA metabolism.Entities:
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Year: 2002 PMID： 12079836 DOI： 10.1111/j.1749-6632.2002.tb04264.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691