| Literature DB >> 12077401 |
Abstract
Most of our knowledge of transcriptional regulation comes from studies in somatic cells. However, increasing evidence reveals that gene regulation mechanisms are different in haploid germ cells. A number of highly specialized strategies operate during spermatogenesis. These include a unique chromatin reorganization program and the use of distinct promoter elements and specific transcription factors. Deciphering the rules governing transcriptional control during spermatogenesis will provide valuable insights of biomedical importance.Mesh：
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Year: 2002 PMID： 12077401 DOI： 10.1126/science.1070963
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728