Literature DB >> 12075862

Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders.

H Kunugi1, T Kato, R Fukuda, M Tatsumi, T Sakai, S Nanko.   

Abstract

Alterations of G proteins have been implicated in major psychiatric illnesses. A C825T polymorphism of a gene encoding the beta3 subunit of heterotrimeric G proteins (GNB3) was reported to be associated with several pathological conditions, such as hypertension and depressive disorder. We examined whether this polymorphism is associated with functional psychoses in a Japanese sample of 370 schizophrenics, 164 bipolars, 68 depressive patients, and 198 controls. We obtained no evidence for an association of the polymorphism with any diagnostic group.

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Year:  2002        PMID： 12075862     DOI： 10.1007/s007020200018

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  9 in total

1.  Association between a functional polymorphism in the renin-angiotensin system and completed suicide.

Authors:  A Hishimoto; O Shirakawa; N Nishiguchi; T Hashimoto; M Yanagi; H Nushida; Y Ueno; K Maeda
Journal:  J Neural Transm (Vienna)       Date:  2006-06-01       Impact factor: 3.575

2.  The GNB3 C825T polymorphism and depression among subjects with alcohol dependence.

Authors:  A P Prestes; F Z C Marques; M H Hutz; C H D Bau
Journal:  J Neural Transm (Vienna)       Date:  2006-08-08       Impact factor: 3.575

3.  Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression.

Authors:  S Anttila; K Huuhka; M Huuhka; R Rontu; K M Mattila; E Leinonen; T Lehtimäki
Journal:  J Neural Transm (Vienna)       Date:  2006-10-27       Impact factor: 3.575

4.  Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.

Authors:  G Andersen; J Overgaard; A Albrechtsen; C Glümer; K Borch-Johnsen; T Jørgensen; T Hansen; O Pedersen
Journal:  Diabetologia       Date:  2005-11-12       Impact factor: 10.122

5.  Genetic associations of brain structural networks in schizophrenia: a preliminary study.

Authors:  Kanchana Jagannathan; Vince D Calhoun; Joel Gelernter; Michael C Stevens; Jingyu Liu; Federico Bolognani; Andreas Windemuth; Gualberto Ruaño; Michal Assaf; Godfrey D Pearlson
Journal:  Biol Psychiatry       Date:  2010-08-05       Impact factor: 13.382

6.  The C825T Polymorphism of the G-Protein β3 Gene as a Risk Factor for Depression: A Meta-Analysis.

Authors:  Liang Fang; Chanjuan Zhou; Shunjie Bai; Chenglong Huang; Junxi Pan; Ling Wang; Xinfa Wang; Qiang Mao; Lu Sun; Peng Xie
Journal:  PLoS One       Date:  2015-07-06       Impact factor: 3.240

7.  GNB3 and CREB1 gene polymorphisms combined with negative life events increase susceptibility to major depression in a Chinese Han population.

Authors:  Jingsong Ma; Lin Wang; Yanjie Yang; Zhengxue Qiao; Deyu Fang; Xiaohui Qiu; Xiuxian Yang; Xiongzhao Zhu; Jincai He; Hui Pan; Bo Ban; Yan Zhao; Hong Sui
Journal:  PLoS One       Date:  2017-02-22       Impact factor: 3.240

8.  Using literature-based discovery to identify candidate genes for the interaction between myocardial infarction and depression.

Authors:  Zhenguo Dai; Qian Li; Guang Yang; Yini Wang; Yang Liu; Zhilei Zheng; Yingfeng Tu; Shuang Yang; Bo Yu
Journal:  BMC Med Genet       Date:  2019-06-11       Impact factor: 2.103

9.  Association of G-Protein β3 Subunit C825T Polymorphism with Seasonal Variations in Mood and Behavior.

Authors:  Yoon-Ju Nam; Chul-Hyun Cho; Leen Kim; Heon-Jeong Lee
Journal:  Psychiatry Investig       Date:  2017-10-17       Impact factor: 2.505
  9 in total

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